Which contact method best warns families of hidden cholesterol danger?

NCT ID NCT07653555

Not yet recruiting Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two approaches to notify relatives of people diagnosed with familial hypercholesterolemia (FH), a genetic condition causing very high cholesterol. One method lets patients share information themselves; the other has the study team contact relatives directly. Researchers will track how many family members get tested for FH within a year to see which approach works better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cascade testing (direct vs. indirect contact methods)
What this could lead to: If one method works better, it could help more families learn about their inherited risk for high cholesterol and take early action.
What could go wrong: This is a small, early-stage study focused on testing methods, not a treatment. Results may not apply to all populations or healthcare settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

familial hypercholesterolemia Hyperlipoproteinemia Type II

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FAMILIAL HYPERCHOLESTEROLEMIA

Contacts and locations

Locations

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

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