Imperial College London

This study tested whether two existing anti-inflammatory drugs, ruxolitinib and fostamatinib, could help prevent hospitalized COVID-19 pneumonia patients from getting sicker. The goal was to see if these drugs could stop mild or moderate cases from progressing to severe pneumonia…

This study tested whether giving doctors a computer decision-support tool helps patients get better cholesterol management after a heart attack. Over 1,100 patients at hospitals that either used the tool or followed standard care were compared. Researchers wanted to see if the to…

This study tested a targeted radiation treatment for people with neuroendocrine cancer that had spread to the liver and could not be removed by surgery. Doctors injected tiny radioactive beads directly into the liver's blood supply to deliver high-dose radiation to the tumors whi…

This study tested if sending heart attack patients home with special remote monitoring equipment could help them manage their recovery and avoid unnecessary trips back to the hospital. Over 300 patients who recently had a heart attack were randomly assigned to either receive the …

This study tested whether the immunotherapy drug pembrolizumab could help control cancer of unknown primary, where doctors can't identify where the cancer started. The trial included 35 patients in two groups: those who had already tried chemotherapy and those receiving it as the…

This study tested whether a supplement called MitoQ could improve heart function in people with dilated cardiomyopathy, a condition where the heart muscle is weak and enlarged. Over 100 participants were randomly assigned to receive either MitoQ or a placebo pill for several mont…

This study tested if new, non-invasive ultrasound scans could predict whether a surgically created dialysis access point would work properly. Researchers followed 76 patients with kidney failure, using special ultrasound techniques to measure blood vessel stiffness and function b…

This study tested whether a simple, non-invasive ultrasound scan could help doctors better diagnose May-Thurner Syndrome, a condition where a vein in the pelvis is compressed, often causing swelling in the left leg. Researchers scanned 40 adults with and without symptoms, measuri…

This study aimed to find the best simple bedside test for detecting poor leg circulation (peripheral arterial disease) in people with diabetes. Researchers compared several quick tests, like blood pressure measurements in the ankle and toe, against more complex imaging scans. The…

This study tested whether giving the Gardasil 9 HPV vaccine to women right after they had surgery to remove abnormal cervical cells could better prevent future infections and cell problems. Over 1,000 women aged 18-55 who had this surgery were randomly assigned to receive either …

This study looked back at medical records to see how a one-step surgery for gallstones was performed before, during, and after the COVID-19 pandemic. Researchers analyzed data from 237 patients who had this specific procedure. The goal was to understand if the surgery remained a …

This study aimed to understand why older adults are more vulnerable to severe RSV infections by comparing their immune responses to younger people. Researchers intentionally gave a controlled RSV infection to 28 healthy older volunteers (ages 60-75) and monitored their immune cel…

This study aimed to understand how COVID-19 affects people with cancer. Researchers looked back at the medical records of 3,820 cancer patients who also had COVID-19. They tracked symptoms, treatments, and survival to learn which cancer patients are most at risk from the virus.

This study aimed to understand how getting older affects the health of people living with HIV. Researchers followed over 1,300 people in England and Ireland, including HIV-positive adults over and under 50, and a comparison group of HIV-negative adults over 50. The goal was to id…