Immunotherapy shows promise for mysterious cancers

NCT ID NCT03752333

First seen Feb 01, 2026 · Last updated Apr 25, 2026 · Updated 8 times

Summary

This study tested the drug pembrolizumab in 35 adults with cancer of unknown primary (CUP), a type of cancer where doctors cannot find where it started. The goal was to see if the drug could shrink tumors and improve survival. Participants received pembrolizumab intravenously, either as their first treatment or after other treatments had failed.

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Contacts and locations

Locations

  • Gastrointestinal Units - The Royal Marsden Hospitals at Sutton and London

    Sutton, Surrey, United Kingdom

  • Guy's Cancer Centre

    London, United Kingdom

  • Hammersmith Hospital

    London, W12 0HS, United Kingdom

Conditions

Explore the condition pages connected to this study.