Heart stent passes Real-World test: orsiro keeps arteries open
NCT ID NCT04175626
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 556 people with coronary artery disease to confirm that the Orsiro drug-eluting stent is safe and effective in everyday use. The stent releases sirolimus to prevent artery re-narrowing. Researchers tracked how many patients had heart-related death, heart attack, or needed another procedure within 12 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Orsiro sirolimus-eluting coronary stent (a metal stent coated with the drug sirolimus)
What this could lead to
If successful, this confirms that the Orsiro stent works well in everyday patients, offering a reliable option to keep heart arteries open and reduce the need for repeat procedures.
What could go wrong
This is a post-approval study confirming earlier results, not a new breakthrough. Stents still carry risks like blood clots or re-narrowing, and results may vary in complex cases.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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AdventHealth Tampa
Tampa, Florida, 33613, United States
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Advocate Lutheran General Hospital
Park Ridge, Illinois, 60068, United States
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AnMed Health
Anderson, South Carolina, 29621, United States
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Ascension St. Vincent Medical Group
Indianapolis, Indiana, 46920, United States
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Ascension Via Christi Hospitals
Wichita, Kansas, 67226, United States
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Austin Heart
Austin, Texas, 78756, United States
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Baylor Heart and Vascular Hospital
Dallas, Texas, 75226, United States
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Baystate Medical Center
Springfield, Massachusetts, 01199, United States
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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Cardiology Associates of Mobile
Fairhope, Alabama, 36532, United States
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Charleston Area Medical Center Memorial Hospital
Charleston, West Virginia, 25304, United States
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Columbia University Medical Center
New York, New York, 10032, United States
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John Muir Medical Center
Concord, California, 94520, United States
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Maimonides Medical Center
Brooklyn, New York, 11219, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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MedStar Union Memorial Hospital
Baltimore, Maryland, 21218, United States
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MedStar Washington Hospital Center
Washington D.C., District of Columbia, 20010, United States
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Mercy Health - St Vincent Medical Center
Toledo, Ohio, 43608, United States
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Minneapolis Heart Institute
Minneapolis, Minnesota, 55407, United States
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Northern Light Cardiology
Bangor, Maine, 04401, United States
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Penn State Health Holy Spirit Medical Center
Camp Hill, Pennsylvania, 17011, United States
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Piedmont Heart Institute
Atlanta, Georgia, 30309, United States
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Saint Michael's Medical Center
Newark, New Jersey, 07102, United States
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Seton Medical Center Austin
Austin, Texas, 78705, United States
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St. Joseph Hospital Orange
Orange, California, 92868, United States
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UT Health Science Center
Houston, Texas, 77030, United States
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University of Chicago Medical Center
Chicago, Illinois, 60637, United States
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University of Illinois
Chicago, Illinois, 60612, United States
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University of Kentucky
Lexington, Kentucky, 40536, United States
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University of Michigan Medical Center
Ann Arbor, Michigan, 48109, United States
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University of Virginia Health System
Charlottesville, Virginia, 22908, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
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Weill Cornell Medical College
New York, New York, 10065, United States