ISCHEMIC HEART DISEASE

This study tests a new type of heart stent (a small mesh tube) in 500 people with heart disease who also take blood thinners. These patients have a high risk of bleeding. The new stent is designed to allow a shorter course of anti-clotting drugs, which may lower that risk. The go…

This study looks at 1,560 people with a completely blocked heart artery and reduced blood flow. It compares opening the artery with a stent plus medication versus medication alone. The goal is to see which approach better prevents heart attacks, strokes, and death, and improves q…

This study tests a new type of heart stent that slowly dissolves over time. It is designed for people with long blockages in their coronary arteries. The goal is to see if the stent is safe and effective at keeping arteries open without needing a permanent metal implant.

This study is checking if a medical device called Essential Pro is safe and works well for people with narrowed heart arteries. About 100 people who already got the device as part of their normal care will be followed. Researchers will track serious heart problems like heart atta…

This study looks at whether giving a carbohydrate drink before heart bypass surgery can help control blood sugar in people with type 2 diabetes. About 50 patients will be enrolled. The goal is to see if this simple step reduces insulin resistance and improves recovery.

This study follows over 2,000 patients with coronary artery disease who received a device called Sequent Please Neo during routine care. Researchers want to confirm the device is safe and works well by tracking major heart problems like heart attacks or the need for repeat proced…

This study looks at how well the SUPRAFLEX CRUZ stent works in people with blocked heart arteries. About 508 adults who already got the stent as part of their normal care will be followed for 12 months. Researchers will track serious heart problems like heart attacks or the need …

This study is testing a very long stent (a mesh tube) to treat long blockages in the heart's arteries. About 1,000 people with coronary artery disease will get one long stent instead of multiple shorter ones. The goal is to see if this approach is safe and works well at keeping t…

This study is checking how well a new drug-coated heart stent (Coroflex ISAR NEO) works and how safe it is in 3,000 people with narrowed heart arteries. Participants get the stent as part of their regular care, and doctors will track heart-related events like heart attacks or the…

This study looks at people who recently had a major heart attack (STEMI) and have multiple blocked arteries. Doctors want to see if placing stents in unstable-looking plaques (that aren't severely blocking blood flow) plus medication is better than medication alone to prevent fut…

This study tests a new type of heart stent made from magnesium that slowly dissolves over time, compared to a permanent metal stent. The goal is to see if the dissolvable stent is safe and works as well for people with blocked heart arteries. About 1,859 adults with coronary arte…

This study tests whether artificial intelligence (AI) can help doctors interpret heart ultrasound (echo) images more accurately and quickly. Researchers at Mayo Clinic will deploy AI tools to assist in diagnosing conditions like cardiomyopathy, coronary artery disease, and cardia…

This study tests whether a special map (dynamic coronary roadmap) helps doctors place a pressure wire in heart arteries faster. About 226 adults with narrowed heart arteries (50-90% blockage) will be randomly assigned to use the map or not during standard pressure tests. The main…

This study looks at whether opening a blocked heart artery 12 to 36 hours after a heart attack can help the heart recover. It involves 150 stable patients who will be randomly assigned to get the procedure right away or wait a few days. The goal is to see if earlier treatment sav…

This study looks at whether a common heart procedure (using the wrist artery) can damage nerves in the hand. Researchers will check 400 people for signs of carpal tunnel syndrome and other nerve problems. The goal is to understand the risks so doctors can better inform patients.

This study aims to improve how we detect and understand heart disease using advanced MRI scans. Researchers will compare new MRI techniques with standard tests in 1,000 adults, both healthy volunteers and those with various heart conditions. The goal is to find better ways to see…

This study looks at whether a special heart scan (coronary CT angiography) is better than standard follow-up care for high-risk patients who have had a stent placed to open blocked arteries. About 3,500 adults aged 19 and older with complex heart conditions will be enrolled. The …

This study tests a new MRI method that tracks how heart cells process sugar, aiming to tell healthy from damaged tissue in people with ischemic heart disease. About 15 participants with chronic heart failure will undergo this special MRI along with standard scans. The goal is to …

This study aims to validate and check the reproducibility of laboratory tests, equipment, and techniques used in research on chronic diseases like obesity, diabetes, and heart disease. Researchers will compare old and new testing methods to ensure results are accurate and consist…

This study is testing a mobile app called GeriKit to see if it can help doctors better understand the health of older adults (75+) with heart disease. Researchers will track things like hospital readmissions and quality of life over 6 months. The goal is to improve care for this …

This study follows 2000 adults with suspected coronary artery disease who have had special imaging or pressure tests inside their heart arteries. Researchers will track major heart events like death, heart attack, or repeat procedures over many years. The goal is to learn which f…