Cord blood stem cells aim to repair damaged hearts

NCT ID NCT06145035

Recruiting now Disease control Sponsor: Roberto Bolli Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether stem cells from umbilical cords can safely improve heart function in people with heart failure due to blocked arteries. Sixty participants will receive either one or two doses of stem cells or a placebo through an IV. The main goal is to see if the heart's pumping ability improves after 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: umbilical cord stem cells
What this could lead to: If successful, this could lead to a new treatment that improves heart function in people with heart failure caused by blocked arteries.
What could go wrong: This is an early Phase 2 trial with only 60 people, so results may not apply to everyone. Stem cell treatments can have unknown long-term effects, and the improvement in heart function may be small or not lasting.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

myocardial ischemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ISCHEMIC HEART DISEASE

Contacts and locations

Locations

The Texas Heart Institute Houston Texas
RECRUITING

Houston, Texas, 77030, United States
University of Louisville School of Medicine, Institute of Molecular Cardiology
RECRUITING

Louisville, Kentucky, 40202, United States
University of Miami Miller School of Medicine
RECRUITING

Miami, Florida, 33136, United States

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