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Dental repair may boost heart and metabolic health

NCT ID NCT07705672

Disease control Sponsor: Dr. Moaz Mohamed Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time

Summary

This study investigates whether replacing missing teeth with fixed dental prosthetics can improve blood sugar and cholesterol levels in people with ischemic heart disease. Participants aged 45 to 70 with stable heart disease and missing teeth receive the dental treatment. Researchers measure changes in HbA1c and cholesterol six months later to see if better chewing ability leads to better metabolic control.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
fixed prosthodontic rehabilitation (dental prosthetics to replace missing teeth)
What this could lead to
If it works, this could point toward a simple dental treatment that helps manage heart disease and related metabolic issues.
What could go wrong
This is a small, early study without a control group, so results may not be conclusive. The dental procedure itself carries standard risks like infection or discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

90 people

The number who actually took part.

Started

Jan 2024

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

45 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

inclusion criteria * Patients aged 45 to 70 years with diagnosed stable ischemic heart disease. * Patients presenting with partial edentulism and compromised masticatory function due to missing teeth. * Patients indicated for fixed prosthodontic rehabilitation. * Patients with complete clinical records and laboratory data available at baseline and 6 months after treatment. * Patients who provided informed consent for treatment and use of their clinical data. Exclusion criteria * uncontrolled systemic diseases affecting metabolic status (e.g., uncontrolled diabetes mellitus). * acute cardiovascular events or unstable ischemic heart disease. * Patients with conditions affecting oral function other than tooth loss (e.g., neuromuscular disorders). * Patients who received removable prostheses instead of fixed prosthodontic rehabilitation. * Patients with incomplete clinical records or missing baseline or 6-month laboratory data.

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Conditions

The condition(s) this trial relates to.

myocardial ischemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ischemic heart disease

Contacts and locations

Locations

  • Faculty of Medicine

    Tanta, Egypt

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