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Can a higher dose of adenosine sharpen heart scans?

NCT ID NCT06578234

Recruiting now Disease control Sponsor: Region Skane Source: ClinicalTrials.gov ↗

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This trial is testing whether a higher dose of adenosine, a drug used during cardiac MRI to stress the heart, improves blood flow imaging compared to the standard dose. The study includes 180 adults with suspected or known coronary artery disease or heart failure. By comparing the two doses, researchers hope to reduce false results and improve diagnosis and treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Adenosine
What this could lead to
If high-dose adenosine works better, it could improve the accuracy of cardiac MRI stress tests, leading to better diagnosis and treatment decisions for people with coronary artery disease.
What could go wrong
This is a phase 4 trial, but it's still testing a dose difference that may not show a clear benefit. High-dose adenosine may cause more side effects like chest discomfort or shortness of breath.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder heart failure myocardial ischemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC CORONARY SYNDROME CORONARY ARTERY DISEASE ISCHEMIC HEART DISEASE

Contacts and locations

Locations

  • Clinical Physiology, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital

    RECRUITING

    Lund, Sweden

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