ISCHEMIC HEART DISEASE

This study aimed to test whether a gene therapy called VM202RY could help the heart heal after a serious heart attack. The treatment involved injecting the therapy directly into the heart muscle of eligible patients to try to improve blood flow and heart function. The trial was d…

This study is testing a new catheter system designed to help doctors safely navigate through and reopen arteries that are 100% blocked (chronic total occlusions). The device uses special imaging to guide tiny wires through the blockage to restore blood flow. Researchers will enro…

This study is testing whether a one-year course of a dietary supplement called spermidine can help older adults with heart disease. Spermidine is a natural compound found in foods like whole grains and nuts. Researchers will check if it improves heart function, muscle mass, physi…

This early-stage study is testing whether transplanting tiny balls of lab-grown heart muscle cells (made from stem cells) is safe and can help patients with severe heart failure. Ten patients with heart failure caused by poor blood flow to the heart will receive the cell transpla…

This study is a registry that tracks how well a specific drug-coated heart stent (ihtDEStiny) works in everyday medical practice. It will follow 400 patients with blocked heart arteries who receive this stent to see how they fare over time. The main goal is to monitor safety and …

This study compares two similar drug-coated stents used to prop open blocked heart arteries. It will enroll 550 patients in China who need this procedure to see if the newer Resolute Onyx stent performs as well as the established Resolute Integrity stent. Researchers will track p…

This study is testing whether using a temporary heart pump during high-risk stent procedures helps prevent serious complications like heart failure or death. It involves 300 patients with severe coronary artery disease and weakened heart muscle who face higher risks during these …

This study aims to see how three different methods for treating severely hardened heart arteries affect tiny blood vessel flow. It will enroll 30 patients with coronary artery disease who need a stent. Researchers will compare lithotripsy (shockwaves), super-high pressure balloon…

This study is testing the safety and effectiveness of a specific drug-coated heart stent (the Medtronic Resolute Onyx) in Chinese patients with blocked coronary arteries. About 591 participants who are eligible for a standard artery-opening procedure (angioplasty) will receive th…

This study is testing whether using a detailed, high-resolution imaging scan called Optical Coherence Tomography (OCT) during emergency heart attack treatment leads to better long-term results for patients. It will compare OCT-guided procedures to the current standard method that…

This study is testing how well a new, detailed ultrasound scan (called UFR) can identify serious blockages in heart arteries. It compares the new scan's results to a standard diagnostic method in 112 patients with suspected heart disease. The goal is to see if this new imaging te…

This study aimed to test a new support program for adults hospitalized with heart disease. The program would automatically screen patients for social needs like food or housing insecurity and connect them electronically to local community resources. The goal was to see if address…

This study aims to understand why some women experience chest pain and heart stress despite having clear major heart arteries. Researchers are examining 206 women with stable chest pain to see if tiny blood vessel problems, platelet activity, or inflammation might be the cause. T…

This study is observing how doctors in Spain currently use injectable blood-thinning medications during heart stent procedures. It will track about 1,000 patients who receive these injections to see what short-term outcomes occur, like complications or side effects. The goal is t…

This study is a large registry tracking 1,003 adults with suspected heart disease. Its main goal is to understand how problems with the heart's smallest blood vessels affect a patient's long-term health after doctors decide on a treatment plan. It also aims to see if using specia…