New ultrasound test could spot dangerous heart blockages faster

NCT ID NCT05694065

Ongoing Diagnosis Sponsor: Ruijin Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This study is testing a new way to diagnose blocked heart arteries using an ultrasound-based method called Ultrasonic Flow Ratio (UFR). It involves 112 people with suspected heart disease. The goal is to see if UFR can accurately identify significant blockages compared to the current standard test (FFR). If it works, this could make diagnosis quicker and less invasive.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ultrasonic Flow Ratio (UFR) assessment
What this could lead to: If successful, UFR could provide a faster, less invasive way to diagnose significant coronary blockages during standard angiography.
What could go wrong: This is a small, early-stage diagnostic study (112 participants) comparing UFR to an existing reference standard (FFR). It does not test treatment outcomes, so even if accurate, it may not improve patient health directly.

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Conditions

The condition(s) this trial relates to.

myocardial ischemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ISCHEMIC HEART DISEASE

Contacts and locations

Locations

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

Shanghai, Shanghai Municipality, 200025, China

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