Heart pump may protect patients during risky stent procedures

NCT ID NCT05003817

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a temporary heart pump can help high-risk patients during coronary stenting. The pump supports the heart's main chamber during the procedure, aiming to prevent heart failure or death. About 300 patients with severe coronary disease and weak heart muscle will be randomly assigned to receive the pump or standard care. The trial will compare rates of death, stroke, heart attack, and hospital stays.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

percutaneous left ventricular unloading device (a temporary heart pump)

What this could lead to

If it works, this could provide a safer way to perform stenting in high-risk patients, reducing serious complications like heart failure or death.

What could go wrong

This is a Phase 3 trial, but the device itself carries risks like bleeding or leg artery damage, and it is expensive. The benefit over standard care is not yet proven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder myocardial ischemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Guy's and St Thomas' NHS Foundation Trust

    London, SE1 7EH, United Kingdom