Heart attack gene therapy trial pulled before it began

NCT ID NCT03404024

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aimed to test a gene therapy called VM202RY in people who recently had a heart attack. The treatment was injected directly into the heart muscle to help it heal and improve pumping strength. However, the trial was withdrawn before enrolling any participants, so no data on safety or effectiveness were collected.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

VM202RY (a DNA plasmid that produces hepatocyte growth factor)

What this could lead to

If it worked, this could point toward a treatment to help heart muscle recover after a heart attack, potentially improving pumping function.

What could go wrong

The study was withdrawn before any patients were enrolled, so no results are available. Even if tested, early-stage gene therapies often fail to show benefit or may cause side effects like inflammation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute myocardial infarction myocardial ischemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chonnam National University Hospital

    Gwangju, South Korea

  • Ewha Womans University Medical Center

    Seoul, South Korea

  • GangNeung Asan Hospital

    Gangneung, South Korea

  • KyungHee University Medical Center

    Seoul, South Korea