Heart attack gene therapy trial pulled before it began
NCT ID NCT03404024
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aimed to test a gene therapy called VM202RY in people who recently had a heart attack. The treatment was injected directly into the heart muscle to help it heal and improve pumping strength. However, the trial was withdrawn before enrolling any participants, so no data on safety or effectiveness were collected.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- VM202RY (a DNA plasmid that produces hepatocyte growth factor)
- What this could lead to
- If it worked, this could point toward a treatment to help heart muscle recover after a heart attack, potentially improving pumping function.
- What could go wrong
- The study was withdrawn before any patients were enrolled, so no results are available. Even if tested, early-stage gene therapies often fail to show benefit or may cause side effects like inflammation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chonnam National University Hospital
Gwangju, South Korea
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Ewha Womans University Medical Center
Seoul, South Korea
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GangNeung Asan Hospital
Gangneung, South Korea
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KyungHee University Medical Center
Seoul, South Korea
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