Which strategy wins for heart attack patients with multiple blocked arteries?
NCT ID NCT03298659
First seen Aug 14, 2026 · Last updated Aug 14, 2026
Summary
This trial investigates the best way to treat people who have a heart attack and also have other narrowed arteries. It compares doing an immediate procedure to open those other arteries, guided by a pressure wire, versus waiting and using a heart scan to decide later. The goal is to see which approach better prevents future heart problems, like another heart attack or heart failure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Two diagnostic tests: iFR (pressure wire) and stress perfusion CMR (imaging)
- What this could lead to
- If successful, this could establish the best way to treat additional blocked arteries in heart attack patients, potentially reducing the risk of future heart events and improving survival.
- What could go wrong
- The trial is large but results may not apply to all patients. Both strategies carry risks, including procedure-related complications, and the optimal approach may depend on individual patient factors.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Radboudumc
Nijmegen, Netherlands
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Other studies related to the condition(s) this trial covers.
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