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Stenting unstable plaques: a new way to prevent second heart attacks?

NCT ID NCT05599061

Ongoing Disease control Sponsor: Fundación EPIC Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 16, 2026 · Updated 3 times

Summary

This study looks at 600 people who had a major heart attack and have other narrowings in their heart arteries that are not severe but look unstable. Half will get a stent plus medication, and half will get medication alone. The goal is to see if stenting these unstable plaques reduces the chance of another heart attack or death.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Percutaneous coronary intervention (stenting) plus optimal medical treatment
What this could lead to
If it works, this could show that stenting unstable plaques in heart attack patients lowers the risk of future heart attacks or death.
What could go wrong
This is an early-stage trial with 600 participants, so results may not apply to everyone. Stenting carries risks like bleeding or vessel damage, and the benefit over medication alone is not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder Coronary Disease myocardial ischemia ST-elevation myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY DISEASE CORONARY DISEASE ISCHEMIC HEART DISEASE

Contacts and locations

Locations

  • Chu de Toledo

    Guadalajara, Spain

  • H.I.U. Materno Infantil de Las Palmas

    Las Palmas de Gran Canaria, 35016, Spain

  • H.U. de Gran Canaria-Dr. Negrin

    Las Palmas de Gran Canaria, 35010, Spain

  • Hospital Clinic de Barcelona

    Barcelona, 08036, Spain

  • Hospital Clinico Universitario Lozano Blesa

    Zaragoza, 50009, Spain

  • Hospital Clinico Universitario de Salamanca

    Salamanca, 37007, Spain

  • Hospital Clinico Universitario de Santiago de Compostela

    Santiago de Compostela, 15706, Spain

  • Hospital Clinico Universitario de Valencia

    Valencia, 46010, Spain

  • Hospital Clínico Universitario de Valladolid

    Valladolid, 47003, Spain

  • Hospital Del Mar

    Barcelona, 08003, Spain

  • Hospital General Universitario Dr.Balmis

    Alicante, 03010, Spain

  • Hospital General Universitario de Albacete

    Albacete, 02006, Spain

  • Hospital General Universitario de Castellón

    Castellon, 12004, Spain

  • Hospital General Universitario de Ciudad Real

    Ciudad Real, 13005, Spain

  • Hospital General Universitario de Elche

    Elche, 03203, Spain

  • Hospital General Universitario de Valencia

    Valencia, 46014, Spain

  • Hospital La Princesa

    Madrid, 28006, Spain

  • Hospital Universitari Germans Trias I Pujol

    Badalona, 08916, Spain

  • Hospital Universitari I Politecnic La Fe

    Valencia, 46026, Spain

  • Hospital Universitari Joan Xxiii

    Tarragona, 43005, Spain

  • Hospital Universitari Miquel Servet

    Zaragoza, 50009, Spain

  • Hospital Universitari MútuaTerrassa

    Terrassa, 08221, Spain

  • Hospital Universitari Sant Joan D'Alacant

    Alicante, 03550, Spain

  • Hospital Universitari Son Espases

    Palma de Mallorca, 07120, Spain

  • Hospital Universitari Vall Hebron

    Barcelona, 08035, Spain

  • Hospital Universitari de Bellvitge

    L'Hospitalet de Llobregat, Barcelona, 08907, Spain

  • Hospital Universitario 12 Octubre

    Usera, 28041, Spain

  • Hospital Universitario A Coruña

    A Coruña, 15006, Spain

  • Hospital Universitario Central de Asturias

    Oviedo, 33011, Spain

  • Hospital Universitario Gregorio Marañon

    Madrid, 28007, Spain

  • Hospital Universitario Juan Ramon Jimenez

    Huelva, 21005, Spain

  • Hospital Universitario La Paz

    Madrid, 28046, Spain

  • Hospital Universitario Marqués de Valdecilla

    Santander, 39008, Spain

  • Hospital Universitario Nuestra Señora de La Candelaria

    Santa Cruz de Tenerife, 38010, Spain

  • Hospital Universitario Puerta Del Mar

    Cadiz, 11009, Spain

  • Hospital Universitario Puerta de Hierro

    Majadahonda, 28222, Spain

  • Hospital Universitario Reina Sofia de Cordoba

    Córdoba, 14004, Spain

  • Hospital Universitario San Cecilio

    Granada, 18016, Spain

  • Hospital Universitario Virgen Arrixaca

    Murcia, 30120, Spain

  • Hospital Universitario Virgen Del Rocio

    Seville, 41013, Spain

  • Hospital Universitario de Cabueñes

    Gijón, 33394, Spain

  • Hospital Universitario de Donostia

    San Sebastián, 20014, Spain

  • Hospital Universitario de Girona Dr Trueta

    Girona, 17007, Spain

  • Hospital Universitario de Leon

    León, 24001, Spain

  • Hospital Universitario de Navarra

    Pamplona, 31008, Spain

  • Hospital Universitario de Torrevieja

    Torrevieja, 03186, Spain

  • Hospital de Manises

    Manises, 46940, Spain

  • Hospital de Merida

    Mérida, 06800, Spain

  • Hospital de Santa Creu I Sant Pau

    Barcelona, 08025, Spain

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