ISCHEMIC HEART DISEASE

This study tests whether using a computer simulation (virtual stenting) before placing stents in heart arteries can lead to better outcomes than the usual method guided by X-ray images alone. About 1,472 adults with coronary artery disease will be randomly assigned to either the …

This early-phase trial will test whether injecting lab-grown heart muscle cells (made from stem cells) into the heart can safely help people with severe heart failure. Fourteen participants with weak hearts will receive the cells via a catheter. The main goal is to check for side…

This study tests whether a simple, 1-minute electrocardiogram (ECG) analyzed by artificial intelligence can accurately detect significant blockages in the heart's arteries. Researchers will compare the AI's predictions against standard imaging tests in 400 adults. If successful, …

This study compares two ways to diagnose bleeding problems during surgery: a quick bedside test (viscoelastic test) and standard lab tests. The goal is to see which method gives faster results, helping doctors treat bleeding sooner. About 210 adults having high-risk surgeries (li…

This study will compare two types of aerobic exercise—interval training and continuous training—in 48 people with stable coronary artery disease. Participants will exercise twice a week for 8 weeks as part of a cardiac rehab program. Researchers will measure heart efficiency, exe…

This phase 2 trial tests whether a traditional Chinese herbal paste called Chaigui Longmu Ejiao Paste can reduce weekly angina attacks in people with ischemic heart disease. Sixty adults aged 18-75 who have stable angina and are on standard heart medications will take the paste o…

This early-stage study will use advanced PET scans to look at how the brain and body work together in people with and without heart disease. Researchers want to see if blood flow and energy use in different organs change during physical or mental stress. The goal is to better und…

This study will test new MRI methods to find early signs of heart disease in 1000 adults. Researchers want to see if these scans can detect tiny changes in heart muscle before standard tests do. Participants will have MRI scans and blood work, but no treatment is given. The goal …

This study tests whether sending an electronic letter to people with heart disease and high cholesterol encourages them to get their cholesterol checked. Researchers will compare those who receive the letter to those who don't, using national health records to track results. The …