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New camera could save hearts: OCTAVE trial tests smarter stent placement

NCT ID NCT07422688

ENROLLING_BY_INVITATION Disease control Sponsor: Aarhus University Hospital Skejby Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Aug 14, 2026 · Updated 5 times

Summary

This study tests whether using a special camera (OCT) inside the heart's arteries during a heart attack procedure leads to better outcomes than the standard X-ray method. About 3000 people having a heart attack will be randomly assigned to one of the two approaches. The goal is to see if OCT guidance reduces deaths, heart attacks, and strokes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Optical coherence tomography (OCT) imaging guidance during stent placement
What this could lead to
If successful, this could show that using OCT imaging during heart attack procedures reduces the risk of death, heart attacks, and strokes compared to standard X-ray guidance.
What could go wrong
This is a large trial, but OCT is an additional procedure that may not improve outcomes enough to justify its cost and time. There is also a risk of complications from the imaging itself.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute chest syndrome acute coronary syndrome coronary artery disorder myocardial ischemia ST-elevation myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACS (ACUTE CORONARY SYNDROME) ISCHEMIC CORONARY ARTERY DISEASE ISCHEMIC HEART DISEASE

Contacts and locations

Locations

  • Aalborg University Hospital

    Aalborg, 9100, Denmark

  • Aarhus University Hospital Skejby

    Aarhus N, 8200, Denmark

  • Akademiske Sjukhuset

    Uppsala, 75237, Sweden

  • Akerhus University Hospital - AHUS

    Lørenskog, 1478, Norway

  • Hospital Clinic de Barcelona

    Barcelona, 08036, Spain

  • Hospital of Southern Norway, Arendal

    Arendal, 4604, Norway

  • Karolinska Universitetssjukhuset

    Stockholm, 14157, Sweden

  • Latvia Centre of Cardiology

    Riga, LV-1002, Latvia

  • Leuven University Hospital

    Leuven, 3000, Belgium

  • North Karelia Central Hospital

    Joensuu, Finland

  • North-Estonia Medical Centre

    Tallinn, 13419, Estonia

  • Odense University Hospital

    Odense, 5000, Denmark

  • Rigshospitalet

    København Ø, 2100, Denmark

  • Royal Bournemouth Hospital

    Bournemouth, BH77DW, United Kingdom

  • Sahlgrenska University Hospital

    Gothenburg, 41345, Sweden

  • Turin Nord Emergency Hospital

    Turin, 10154, Italy

  • University Hospital of Zürich

    Zurich, 8091, Switzerland

  • Zealand University Hospital, Roskilde Sygehus

    Roskilde, 4000, Denmark

  • Ziekenhuis Oost-Limburg

    Genk, 3600, Belgium

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