Lab-Grown heart cells implanted in 10 patients in bid to repair damaged hearts
NCT ID NCT04945018
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This early-phase trial is testing whether heart muscle cells grown from stem cells can be safely injected into the hearts of 10 people with severe heart failure caused by blocked arteries. The main goal is to check for side effects over 26 weeks, while also measuring whether the treatment improves the heart's pumping ability. If successful, it could lead to larger studies exploring a new repair strategy for failing hearts.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
iPS cell-derived heart muscle cells (HS-001)
What this could lead to
If it works, this could point toward a new way to repair damaged heart muscle in people with severe heart failure, potentially reducing the need for a heart transplant.
What could go wrong
This is a very early, small trial with only 10 participants, so results may not apply to everyone. There are risks from the injection procedure and the cells themselves, such as irregular heartbeats or rejection.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Juntendo University Hospital
Tokyo, Japan
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Nihon University Itabashi Hospital
Tokyo, Japan
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Saitama Medical University International Medical Center
Saitama, Japan
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St. Marianna University Hospital
Kawasaki, Japan
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The University of Tokyo Hospital
Tokyo, Japan
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Tokyo Medical and Dental University Medical Hospital
Tokyo, Japan
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Tokyo Metropolitan Geriatric Medical Center
Tokyo, Japan
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Tokyo Women's Medical University
Tokyo, Japan