Could a gentler tug on the Heart's reins spark recovery?
NCT ID NCT03238690
First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time
Summary
This trial tests whether slowly lowering the speed of a Left Ventricular Assist Device (LVAD) — a mechanical pump that helps a failing heart — can encourage the heart muscle to work harder and recover. The study enrolls people with end-stage heart failure who are waiting for a heart transplant. Over several visits, the LVAD speed is gradually reduced, and heart function is measured to see if this 'conditioning' approach improves the heart's pumping ability.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Controlled Cardiac Reloading through LVAD Speed Adjustment
- What this could lead to
- If successful, this approach could help some heart failure patients recover enough heart function to potentially reduce or avoid the need for a transplant.
- What could go wrong
- This is an early-stage study with a historical comparison group, not a randomized controlled trial. Results may not apply to all patients, and reducing LVAD support carries risks like heart failure worsening or blood clots.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
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