Heart artery blockage study: stent or meds – which is better?

NCT ID NCT03563417

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two approaches for people with a completely blocked heart artery (chronic total occlusion) that is causing reduced blood flow to the heart muscle. One group will receive a stent to open the blockage, while the other will take medications only. The goal is to see which strategy better prevents major heart problems and improves quality of life. About 1,560 adults with stable heart disease are being enrolled.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aarhus University Hospital

    RECRUITING

    Aarhus N, 8200, Denmark

  • Barts Health NHS

    ACTIVE_NOT_RECRUITING

    London, SW17 0QT, United Kingdom

  • Belfast Health and Social Care Trust, Department of Cardiology

    ACTIVE_NOT_RECRUITING

    Belfast, BT9 7AB, United Kingdom

  • Cardiovascular Institute, Groupe Hospitalier Mutualiste

    RECRUITING

    Grenoble, 38000, France

  • Clinique Louis Pasteur

    ACTIVE_NOT_RECRUITING

    Essey-lès-Nancy, 54270, France

  • Gentofte Hospital

    RECRUITING

    Hellerup, 2900, Denmark

  • Heart Hospital Tampere

    RECRUITING

    Tampere, 33520, Finland

  • Helsinki University Central Hospital

    ACTIVE_NOT_RECRUITING

    Helsinki, 00029, Finland

  • Hospital Clinic

    RECRUITING

    Barcelona, 08036, Spain

  • Hospital Galdakao

    RECRUITING

    Galdakao, Bizkaia, 48960, Spain

  • Hospital Germans Trias I Pujol

    ACTIVE_NOT_RECRUITING

    Badalona, Barcelona, 08916, Spain

  • Hospital Universitari de Tarragona Joan XXIII

    RECRUITING

    Tarragona, 43005, Spain

  • Hospital Universitario Clinico San Carlos

    RECRUITING

    Madrid, 28040, Spain

  • Hospital Vall de Hebron

    ACTIVE_NOT_RECRUITING

    Barcelona, 08035, Spain

  • Hospital de Bellvitge

    ACTIVE_NOT_RECRUITING

    Barcelona, 08907, Spain

  • Hospital la Paz

    ACTIVE_NOT_RECRUITING

    Madrid, 28046, Spain

  • Kuopio University Hospital

    ACTIVE_NOT_RECRUITING

    Kuopio, 70210, Finland

  • North-Estonia Medical Centre

    RECRUITING

    Tallinn, 13419, Estonia

  • Odense University Hospital

    RECRUITING

    Odense, 5000, Denmark

  • Rigshospitalet

    RECRUITING

    Copenhagen, 2100, Denmark

  • Sahlgrenska University Hospital

    RECRUITING

    Gothenburg, 41345, Sweden

  • Skaane University Hospital (Lund)

    ACTIVE_NOT_RECRUITING

    Lund, 22185, Sweden

  • St George's University Hospital

    ACTIVE_NOT_RECRUITING

    London, SW17 0QT, United Kingdom

  • Stockholm South Central Hospital (Södersjukhuset)

    ACTIVE_NOT_RECRUITING

    Stockholm, 11883, Sweden

  • Turku University Hospital

    RECRUITING

    Turku, 20521, Finland

  • University Hospital Bristol

    ACTIVE_NOT_RECRUITING

    Bristol, BS1 3NU, United Kingdom

  • Zealand University Hospital

    RECRUITING

    Roskilde, 4000, Denmark

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