MYOCARDIAL ISCHEMIA

This study compares two imaging methods to guide stent placement in people with calcium buildup in their heart arteries. About 700 adults with signs of reduced blood flow to the heart will be randomly assigned to have their procedure guided by either a coronary CT angiogram or th…

This study tests a new type of heart stent that slowly dissolves over time. It is designed for people with long blockages in their coronary arteries. The goal is to see if the stent is safe and effective at keeping arteries open without needing a permanent metal implant.

This study is testing a drug called regadenoson in children who need a heart stress test. The drug helps doctors see how well blood flows to the heart. The goal is to check the drug's safety and how the body processes it in different age groups, from infants to teenagers.

This study looks at how well two types of heart stents (Synergy XD and Synergy Megatron) work in everyday medical practice. About 2000 adults with coronary artery disease will receive these stents to open blocked arteries. Researchers will track deaths, heart attacks, and the nee…

This study looks at whether using just one blood thinner (single antiplatelet therapy) is safer and as effective as using two (dual antiplatelet therapy) in older adults or those at high risk of bleeding who have had a heart procedure with a drug-coated balloon. About 576 partici…

This study tests a new type of heart stent made from magnesium that slowly dissolves over time, compared to a permanent metal stent. The goal is to see if the dissolvable stent is safe and works as well for people with blocked heart arteries. About 1,859 adults with coronary arte…

This study aims to speed up and improve the diagnosis of a rare heart condition where a coronary artery grows from the wrong spot, which can cause sudden cardiac death in young athletes. Researchers will use artificial intelligence and 3D computer models to analyze CT scans and p…

This study tests a new smartphone-based 12-lead ECG device to see if it can accurately detect heart attacks (STEMI and NSTEMI) compared to standard hospital ECGs. About 1,000 adults with chest pain will be enrolled in emergency departments. The goal is to validate the device as a…

This study looks at a new computer program that helps doctors diagnose blocked heart arteries from CT scans more accurately. It combines several checks into one step, which may reduce the need for invasive tests. Researchers will review past scans from 1,000 patients to see if th…

This early study tests a device called the A-FLUX Reducer, placed in a heart vein, to improve chest pain in 30 adults with microvascular angina (small vessel heart disease). The goal is to see if it is safe and can reduce symptoms. Participants must have had persistent chest pain…

This study looks at 570 people with chronic coronary syndrome (ongoing chest pain or discomfort due to narrowed heart arteries). Participants get a special PET scan to check blood flow. Those with abnormal results are randomly assigned to either immediate heart catheterization or…

This study tests whether adding special breathing exercises (inspiratory muscle training) to standard cardiac rehab helps people with heart disease recover better. About 72 adults who had a heart procedure called angioplasty will take part. The goal is to see if this extra traini…

This study is for adults with psoriasis who want to help researchers understand the link between psoriasis and heart disease. The goal is to see if certain heart tests and blood markers can predict future heart problems. Participants will be followed over time to track heart heal…

This study will use artificial intelligence to analyze heart CT scans from 10,000 adults to better predict who is at risk for a heart attack. Participants will have a CT scan, blood tests, and answer health questions. The goal is to see if AI can find hidden signs of heart diseas…

This study looks at how modern, minimally invasive lung cancer surgery affects the heart's electrical signals and stress levels. Researchers will monitor 100 adult patients before, during, and after surgery to see if any heart changes occur and if they are temporary. The goal is …

This study looks at whether a sensitive blood test (high-sensitive troponin I) can spot heart muscle damage in patients having below-knee surgery with a nerve block. Researchers will measure troponin levels during surgery and at 24 and 48 hours after. The goal is to better unders…