CT scans could make heart stent surgery safer and faster

NCT ID NCT07286578

Recruiting now Disease control Sponsor: Fundación EPIC Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 11, 2026 · Updated 5 times

Summary

This study tests whether using a CT scan to guide heart stent placement is better than the current standard (IVUS ultrasound) for people with hardened, calcified coronary arteries. About 700 adults with evidence of reduced blood flow to the heart will be randomly assigned to one of the two imaging methods. The goal is to see if CT guidance leads to better stent expansion and similar or fewer heart problems over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CT-guided percutaneous coronary intervention (stent placement) compared to IVUS-guided percutaneous coronary intervention
What this could lead to: If successful, CT guidance could make heart stent procedures faster and more effective for patients with calcified arteries, potentially reducing complications.
What could go wrong: This is a mid-stage trial with 700 participants, so results may not apply to all patients. CT guidance might not improve outcomes or could have unforeseen risks.

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Conditions

The condition(s) this trial relates to.

Arterial Occlusive Diseases arteriosclerosis disorder cardiovascular disorder coronary artery disorder coronary atherosclerosis heart disorder myocardial ischemia vascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARTERIAL OCCLUSIVE DISEASES ARTERIOSCLEROSIS CARDIOVASCULAR DISEASES CORONARY ARTERY DISEASE HEART DISEASES MYOCARDIAL ISCHEMIA VASCULAR DISEASES

Contacts and locations

Locations

Azorg Hospital, Aalst
RECRUITING

Aalst, 9300, Belgium
Bringham and Women's Hospital
NOT_YET_RECRUITING

Boston, Massachusetts, 02115, United States
Columbia University Irving Medical Center/NewYork-Presbyterian Hospital
NOT_YET_RECRUITING

New York, New York, 10032, United States
HACKENSACK MERIDIAN HEALTH, Inc
NOT_YET_RECRUITING

Jersey City, New Jersey, 08837, United States
Hospital Universitari Vall Hebron
RECRUITING

Barcelona, 08035, Spain
Hospital Universitario La Paz
RECRUITING

Madrid, 28046, Spain
Hospital Universitario de Leon
RECRUITING

León, Spain
John Radcliffe Hospital, Oxford
NOT_YET_RECRUITING

Oxford, United Kingdom
Minneapolis Heart Institute
RECRUITING

Minneapolis, Minnesota, 55407, United States
Newcastle Hospitals NHS Foundations Trust
NOT_YET_RECRUITING

Newcastle, United Kingdom
St Bartholomew's Hospital (Barts Health NHS Trust)
RECRUITING

London, United Kingdom
St George's University Hospitals NHS Foundations Trust
RECRUITING

London, United Kingdom
University Hospitals of Leicester NHS Trust
RECRUITING

Leicester, United Kingdom
Weill Medical College of Cornell University
NOT_YET_RECRUITING

New York, New York, 14853, United States

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