Heart study: is early catheterization better than drugs for chest pain?

NCT ID NCT05865600

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at 570 people with chronic coronary syndrome (chest pain or shortness of breath due to narrowed heart arteries). Participants with abnormal blood flow on a PET scan will be randomly assigned to either immediate heart catheterization or a 3-month delay, while both groups receive optimized heart medications. The goal is to see which approach better relieves symptoms after 3 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

guideline-directed medical therapy (heart medications) and invasive coronary angiography (heart catheterization)

What this could lead to

If it works, this could show that early heart catheterization is better than medication alone for relieving chest pain in people with chronic coronary syndrome.

What could go wrong

This is a medium-sized trial (570 people) and results may not apply to everyone. The benefit of early catheterization may be small or not outweigh risks like complications from the procedure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Angina Pectoris Angina, Stable coronary artery disorder myocardial ischemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Gødstrup Hospital

    RECRUITING

    Herning, Central Jutland, 7400, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••