Heart study: is early catheterization better than drugs for chest pain?
NCT ID NCT05865600
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at 570 people with chronic coronary syndrome (chest pain or shortness of breath due to narrowed heart arteries). Participants with abnormal blood flow on a PET scan will be randomly assigned to either immediate heart catheterization or a 3-month delay, while both groups receive optimized heart medications. The goal is to see which approach better relieves symptoms after 3 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- guideline-directed medical therapy (heart medications) and invasive coronary angiography (heart catheterization)
- What this could lead to
- If it works, this could show that early heart catheterization is better than medication alone for relieving chest pain in people with chronic coronary syndrome.
- What could go wrong
- This is a medium-sized trial (570 people) and results may not apply to everyone. The benefit of early catheterization may be small or not outweigh risks like complications from the procedure.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Gødstrup Hospital
RECRUITINGHerning, Central Jutland, 7400, Denmark
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