Could a simple scan replace invasive heart imaging before bypass surgery?

NCT ID NCT07769008

First seen Aug 17, 2026 · Last updated Aug 17, 2026

Summary

This trial tests whether planning coronary artery bypass grafting (CABG) using a non-invasive CT scan (CCTA) works as well as the standard invasive angiography (CAG). About 826 people with blocked heart arteries will be randomly assigned to have their surgery planned with one of the two imaging methods. The main goal is to compare major heart-related events within one year, such as heart attacks, strokes, and repeat procedures. If CCTA proves non-inferior, it could offer a safer, more comfortable alternative for surgical planning.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Coronary computed tomography angiography (CCTA) as a surgical planning tool
What this could lead to
If successful, this could make bypass surgery planning less invasive and more accessible, potentially reducing risks and improving recovery.
What could go wrong
The trial is still in progress, and results may not show non-inferiority. CCTA may miss details that invasive angiography captures, and the approach may not suit all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ruijin Hospital Shanghai Jiao Tong University School of Medicine

    RECRUITING

    Shanghai, China

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