Tiny implant aims to relieve chest pain when Heart's small vessels fail

NCT ID NCT07449325

Recruiting now Disease control Sponsor: VahatiCor, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 16, 2026 · Updated 4 times

Summary

This early study tests a device called the A-FLUX Reducer, which is implanted into a vein in the heart to help blood flow. It is for people with chest pain caused by problems in the heart's tiny blood vessels (microvascular dysfunction). The study will enroll 30 adults and focus mainly on safety and whether the device can be placed correctly.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: A-FLUX Reducer System (implantable nitinol device)
What this could lead to: If it works, this device could offer a new way to reduce chest pain in people with microvascular angina who have few other options.
What could go wrong: This is a very early, small safety study with only 30 people. The device may not improve symptoms, and risks include heart damage or device movement.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Angina Pectoris cardiovascular disorder coronary microvascular disorder heart disorder intermediate coronary syndrome Microvascular Angina myocardial ischemia vascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANGINA PECTORIS CARDIOVASCULAR DISEASES HEART DISEASES MICROVASCULAR ANGINA MYOCARDIAL ISCHEMIA VASCULAR DISEASES

Contacts and locations

Locations

The Cleveland Clinic Foundation
RECRUITING

Cleveland, Ohio, 44195, United States
The Lindner Research Center at The Christ Hospital
RECRUITING

Cincinnati, Ohio, 45219, United States
Yale University
RECRUITING

New Haven, Connecticut, 06511, United States

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