Tiny implant aims to relieve chest pain when Heart's small vessels fail
NCT ID NCT07449325
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This early study tests a device called the A-FLUX Reducer, which is implanted into a vein in the heart to help blood flow. It is for people with chest pain caused by problems in the heart's tiny blood vessels (microvascular dysfunction). The study will enroll 30 adults and focus mainly on safety and whether the device can be placed correctly.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
A-FLUX Reducer System (implantable nitinol device)
What this could lead to
If it works, this device could offer a new way to reduce chest pain in people with microvascular angina who have few other options.
What could go wrong
This is a very early, small safety study with only 30 people. The device may not improve symptoms, and risks include heart damage or device movement.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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The Lindner Research Center at The Christ Hospital
RECRUITINGCincinnati, Ohio, 45219, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Yale University
RECRUITINGNew Haven, Connecticut, 06511, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact