Could High-Intensity workouts and diet tame chest pain from tiny heart vessels?
NCT ID NCT06681896
First seen Aug 14, 2026 · Last updated Aug 14, 2026
Summary
This trial tests whether a 24-week personalized program called MICROFIT—combining high-intensity interval training with a personal trainer and Mediterranean-style dietary advice—is feasible for people with microvascular coronary dysfunction, a condition where small heart blood vessels don't work properly, causing chest pain. About 40 participants will be randomly assigned to either MICROFIT plus usual care or usual care alone. The study focuses on whether people can stick with the program and whether it shows promise in reducing angina symptoms, as measured by questionnaires and heart tests.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- MICROFIT - a 24-week personalized program combining high-intensity interval training (HIIT) with a personal trainer and Mediterranean-style dietary advice
- What this could lead to
- If this program proves feasible and shows promise, it could lead to a larger trial testing whether exercise and diet can reduce chest pain and improve quality of life in people with microvascular angina.
- What could go wrong
- This is a small feasibility study, so results may not be conclusive. The exercise program is intense and may be hard for some to stick with, and it's unclear if it will meaningfully reduce symptoms.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Royal United Hospitals Bath NHS Foundation Trust
RECRUITINGBath, BA1 3NG, United Kingdom
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University Hospitals Bristol and Weston NHS Foundation Trust
RECRUITINGBristol, BS2 8ED, United Kingdom
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