Could a blood pressure drug ease chest pain in people with clear arteries?
NCT ID NCT07670091
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether bosentan, a drug that blocks a natural vessel-constricting substance, can improve blood flow in the tiny heart vessels of people with angina who have no major blockages. About 45 participants will get bosentan for 4 weeks and have MRI scans before and after. The goal is to understand if this approach could lead to new treatments for microvascular angina.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Bosentan (endothelin receptor antagonist)
What this could lead to
If it works, this could point toward a new treatment for angina caused by small vessel problems, not just blocked arteries.
What could go wrong
This is a very small, early study (45 people) looking at blood flow changes, not symptoms. Bosentan may not improve angina or could have side effects.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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NHS University Hospitals of Liverpool Group
Liverpool, United Kingdom