MYOCARDIAL ISCHEMIA

This study tested a program to help veterans with heart disease or rheumatic conditions take their medications as prescribed. Over 5,000 participants received reminders via text or phone calls, with extra support if needed. The goal was to improve medication adherence and reduce …

This study looked at 556 people with coronary artery disease to confirm that the Orsiro drug-eluting stent is safe and effective in everyday use. The stent releases sirolimus to prevent artery re-narrowing. Researchers tracked how many patients had heart-related death, heart atta…

This study tested a very small balloon catheter (Sapphire 3) in 170 people with severely blocked heart arteries (chronic total occlusions). The balloon was used to open the blockage before placing a stent. The main goal was to see if the device could be safely delivered, inflated…

This study tested a virtual cardiac rehabilitation program using a smartphone app, a fitness wristband, and a blood pressure monitor for people who recently had a heart attack, heart surgery, or a stent. The goal was to see if this home-based program could improve walking ability…

This completed trial tested whether taking two blood thinners (clopidogrel and aspirin) for 12 months after a heart stent procedure is better than aspirin alone for people with multiple blocked coronary arteries. Over 8,000 patients were enrolled across 100 centers. The main goal…

This study tested whether patient education and activity-based training help people recover daily living skills after a heart attack. 42 participants who had a heart attack with good heart function received one-on-one education at discharge and again two weeks later. The goal was…

This study looked at two different heart stents (tiny mesh tubes used to open blocked arteries) to see which one works better in routine hospital care. Over 1,000 patients who needed a stent took part. The goal was to compare costs, procedure time, and how many extra devices were…

This study looked at how men and women's brains and hearts react to mental stress. Researchers used special brain and heart scans on 64 healthy adults aged 50-75. The goal was to understand if stress affects heart health differently based on sex. No treatment was given; this was …

This completed study looked at how much radiation people receive during heart CT scans (CCTA) in everyday hospital practice. Researchers enrolled 66 adults who needed a heart CT and recorded the radiation dose used, along with any dose-saving techniques. The goal was to understan…

This study looked at 80 adults having heart valve or aortic surgery to find out how long a special heart protection solution (Del Nido cardioplegia) keeps the heart safe during surgery. Researchers took blood samples at set times to see when heart injury began. The goal was to le…

This study looked at whether the time of day a person has heart surgery changes how their heart muscle tolerates the stress of the procedure. Researchers took small tissue samples from the hearts of 88 patients having planned heart surgery, either in the morning or afternoon. The…

This study looked at 1,695 people with stable heart disease affecting multiple arteries. Researchers compared long-term outcomes for those who had bypass surgery, stents, or took medication only. The goal was to see which approach best prevents heart attacks and heart-related dea…

This study looked at how well a special heart MRI (called stress CMR) finds blocked arteries in real hospitals, not just research centers. Researchers tracked 2,349 people aged 35-85 who had symptoms of heart disease. They recorded heart attacks, deaths, and hospital visits to se…

This study looked at whether silent myocardial ischemia (reduced blood flow to the heart without chest pain) increases the risk of heart problems or death in people with coronary heart disease. Researchers followed participants for one to three years. The goal was to better under…

This study tested new MRI methods to detect bleeding inside the heart muscle after a heart attack. Researchers studied 14 patients to see if these scans could better identify damage that raises the risk of heart failure. The goal was to improve imaging, not to test a treatment.