Heart drug for kids? new study tests safety of regadenoson in young patients

NCT ID NCT04604782

Recruiting now Knowledge-focused Sponsor: GE Healthcare Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a drug called regadenoson in children who need a special heart MRI. The drug helps doctors see how well blood flows to the heart during a stress test. Researchers want to find the right dose and make sure it is safe for kids of different ages, from infants to teenagers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Regadenoson (Rapiscan)
What this could lead to: If successful, this could help doctors use regadenoson safely in children during heart stress tests, improving diagnosis of heart problems.
What could go wrong: This is an early-phase study with only 54 children. It focuses on safety and dosing, not on treating disease. Side effects or lack of effectiveness in this age group are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder myocardial ischemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY DISEASE MYOCARDIAL ISCHEMIA

Contacts and locations

Locations

Bambino Gesu Children Hospital
RECRUITING

Roma, 00165, Italy
Bristol Royal Hospital for Children
NOT_YET_RECRUITING

Bristol, BS28BJ, United Kingdom
King's College London, Rayne Institute
RECRUITING

London, SE1 7EH, United Kingdom
Mitera Hospital
COMPLETED

Athens, 15123, Greece
Paris Public Hospitals System; Necker Hospital for Sick Children
TERMINATED

Paris, 75015, France

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