Can a simple score shorten blood thinner use after a heart attack?
NCT ID NCT06216821
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether a risk score (OPT-CAD) can safely guide how long heart attack patients need to take two blood thinners after getting a stent. About 3,490 participants will either follow standard 12-month dual therapy or have their therapy reduced to one blood thinner earlier (1 month for low-risk, 3 months for higher-risk). The goal is to see if this personalized approach lowers the combined risk of death, heart attack, stroke, stent clots, and major bleeding.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dual antiplatelet therapy (aspirin and a P2Y12 inhibitor) with de-escalation to a single P2Y12 inhibitor
What this could lead to
If successful, this could provide a personalized approach to shorten the time patients need to take two blood thinners after a heart attack, reducing bleeding risk while still preventing clots.
What could go wrong
This is a single-country, open-label trial, so results may not apply globally. The risk score is new and may not accurately predict outcomes for all patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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General Hospital of Northern Theater Command
RECRUITINGShenyang, Liaoning, 110016, China
Contact Phone: •••-•••-•••• Email: •••••@•••••