Early valve repair after heart attack may save lives

NCT ID NCT06282042

First seen Oct 31, 2025 · Last updated May 05, 2026 · Updated 23 times

Summary

This study tests whether repairing a leaky mitral valve soon after a heart attack can reduce the risk of death and heart failure hospitalizations. It includes 250 adults with moderate to severe valve leakage. The approach uses a catheter-based procedure to clip the valve, aiming to improve survival and quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

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Locations

  • Amphia Hospital

    NOT_YET_RECRUITING

    Breda, Breda, 4818 CK, Netherlands

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  • Amsterdam University Medical Center

    NOT_YET_RECRUITING

    Amsterdam, Amsterdam, 1081 HV, Netherlands

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  • Catharina Ziekenhuis Hospital

    NOT_YET_RECRUITING

    Eindhoven, Eindhoven, 5623 EJ, Netherlands

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  • Centro Cardiológico Monzino

    NOT_YET_RECRUITING

    Milan, Milan, 20138, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • Civil Hospital of Brescia

    NOT_YET_RECRUITING

    Brescia, Brescia, 25123, Italy

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  • Emek Medical Center

    NOT_YET_RECRUITING

    Afula, Afula, 1834111, Israel

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  • Erasmus University Medical Center

    NOT_YET_RECRUITING

    Rotterdam, Rotterdam, 3015 GD, Netherlands

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  • Hospital Clínic Barcelona

    NOT_YET_RECRUITING

    Barcelona, Barcelona, 08036, Spain

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  • Hospital Clínico Universitario San Carlos

    NOT_YET_RECRUITING

    Madrid, Madrid, 28040, Spain

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  • Hospital Clínico Universitario de Valladolid

    NOT_YET_RECRUITING

    Valladolid, Valladolid, 47003, Spain

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  • Hospital General Universitario Dr. Balmis

    NOT_YET_RECRUITING

    Alicante, Alicante, 03010, Spain

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  • Hospital Universitario Central de Asturias (HUCA)

    RECRUITING

    Oviedo, Principality of Asturias, 33011, Spain

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  • Hospital Universitario Doctor Negrin

    NOT_YET_RECRUITING

    Las Palmas de Gran Canaria, Las Palmas, 35010, Spain

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  • Hospital Universitario Marqués de Valdecilla

    NOT_YET_RECRUITING

    Santander, Cantabria, 39008, Spain

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  • Hospital Universitario Puerta de Hierro

    NOT_YET_RECRUITING

    Madrid, Madrid, 28222, Spain

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  • Hospital Universitario Ramón y Cajal

    NOT_YET_RECRUITING

    Madrid, Madrid, 28034, Spain

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  • Hospital Universitario Reina Sofía

    NOT_YET_RECRUITING

    Córdoba, Córdoba, 14004, Spain

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  • Hospital Universitario Vall d'Hebrón

    NOT_YET_RECRUITING

    Barcelona, Barcelona, 08035, Spain

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  • Hospital Universitario Virgen de la Victoria

    NOT_YET_RECRUITING

    Málaga, Málaga, 29010, Spain

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  • Hospital Universitario de Bellvitge

    NOT_YET_RECRUITING

    L'Hospitalet de Llobregat, Barcelona, 08907, Spain

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  • Hospital de la Santa Creu i Sant Pau

    NOT_YET_RECRUITING

    Barcelona, Barcelona, 08025, Spain

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  • Hospital Álvaro Cunqueiro

    NOT_YET_RECRUITING

    Vigo, Pontevedra, 36312, Spain

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  • Isala Hospital

    NOT_YET_RECRUITING

    Zwolle, Zwolle, 8025 AB, Netherlands

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  • Leiden University Medical Center

    NOT_YET_RECRUITING

    Leiden, Leiden, 2333 ZA, Netherlands

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  • Maastricht University Medical Center

    NOT_YET_RECRUITING

    Maastricht, Maastricht, 6229 HX, Netherlands

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  • Ospedale Policlinico San Martino

    NOT_YET_RECRUITING

    Genova, Genova, 16132, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • Policlínico San Donato

    NOT_YET_RECRUITING

    San Donato Milanese, San Donato Milanese, 20097, Italy

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  • Rabin Medical Center

    NOT_YET_RECRUITING

    Petah Tikva, Petah Tikva, 4941492, Israel

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  • San Raffaele Hospital

    NOT_YET_RECRUITING

    Milan, Milano, 20132, Italy

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  • Shaare Zedek Medical Center

    RECRUITING

    Jerusalem, Jerusalen, 9103102, Israel

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  • Sheba Medical Center

    NOT_YET_RECRUITING

    Ramat Gan, Ramat Gan, Israel

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  • St. Antonius Hospital

    NOT_YET_RECRUITING

    Nieuwegein, Nieuwegein, 3435 CM, Netherlands

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Conditions

Explore the condition pages connected to this study.