MYOCARDIAL INFARCTION

This study tested a new device that uses sound waves to break up calcium buildup in heart arteries before placing a stent. 145 people with hardened arteries took part. The goal was to see if the device is safe and helps stents work better.

This study looked at whether giving iron through a vein (IV) works better than iron pills to help the heart pump more strongly after a heart attack. It included 298 adults who had a heart attack and also had low iron levels. The main goal was to see if IV iron improved heart wall…

This study tested whether giving atropine, a drug that increases heart rate, could prevent dangerous heart rhythm problems in people having a specific type of heart attack (inferior STEMI) during a procedure to open blocked arteries. 158 participants were included. The goal was t…

This study tested a newer type of heart stent (Xience Sierra) in 1757 people with heart disease, including many with diabetes or prediabetes. The goal was to see if the stent is safe and works well in both general and high-risk patients. Researchers tracked heart-related events l…

This study tested a program called ENHANCE to help people with two or more long-term health problems like HIV, high blood pressure, diabetes, asthma, or depression. Over 1,800 adults aged 40 and older took part. Some clinics used a special decision-support tool and home visits fr…

This study looked at whether getting vitamin D levels to a healthy range after a heart attack could lower the chance of having another heart attack, stroke, heart failure, or death. About 634 heart attack patients took part, with half getting standard care and half getting extra …

This study looked at whether a two-year intensive monitoring program involving nurses, doctors, and pharmacists could improve outcomes for people who had a stroke or heart attack. The program aimed to better control risk factors like high blood pressure and cholesterol, prevent c…

This study looked at whether using a 980nm diode laser along with standard deep cleaning improves gum health and reduces body-wide inflammation in people with gum disease, including those who had a heart attack in the last 6 months. About 80 participants under 70 years old were d…

This study tested whether giving a low dose of a clot-busting drug (tPA) directly into the heart artery during emergency angioplasty improves outcomes for people having a major heart attack. The trial involved 210 participants and compared the drug to a placebo. The goal was to s…

This study looked at 112 adults who had a severe heart attack and multiple blocked arteries. It compared fixing all blockages in one procedure versus doing them in separate sessions. The goal was to see if the one-time approach could shorten hospital stays and lower costs without…

This study tested a single intravenous infusion of stem cells (PROCHYMAL) in 220 adults who had their first heart attack within the past week. The goal was to see if the stem cells could safely improve heart function and reduce damage. Participants were randomly assigned to recei…

This study tested whether dapagliflozin, a diabetes drug, can help people with type 2 diabetes recover better after a heart attack. Researchers measured heart-related events like another heart attack, stroke, or death, as well as inflammation levels. The study included 143 adults…

This study looked at 1,424 veterans with heart problems who had major surgery. It compared giving blood transfusions when hemoglobin drops below 10 (liberal strategy) versus below 7 (restrictive strategy). The goal was to see which approach better prevents serious complications l…

This study tested a mobile app-based cardiac rehab program for people who recently had a heart attack, stent, or heart surgery. 259 participants were randomly assigned to either the app program or traditional center-based rehab. The goal was to see if the app could improve walkin…

This study tested a computer program that helps doctors decide which cholesterol-lowering medicines to prescribe after a heart attack. Over 1,100 patients took part across multiple hospitals. The tool gave doctors personalized risk estimates and treatment suggestions based on gui…

This study looked at how different exercise programs affect fitness and heart scarring in people who had a heart attack. 188 adults, aged 18-75, were assigned to 12 weeks of high-intensity interval training, moderate continuous training, or standard physical activity. The goal wa…

This study tested whether sending educational text messages to people who had a heart attack could help them control risk factors like blood pressure and cholesterol, and prevent future heart problems. 370 patients participated and received text messages for one year. The goal wa…

This study tested a device called a stent retriever, normally used for strokes, to remove blood clots during a heart attack. The goal was to see if it could reduce damage to small blood vessels in the heart better than standard treatment. The trial involved 81 adults having a hea…

This study tested whether the drug henagliflozin, taken for 6 months after a heart attack, can reduce the size of heart muscle damage and improve heart function. 248 adults who had a specific type of heart attack (STEMI) and underwent a procedure to open blocked arteries particip…

This study looked at 10,000 people who came to the emergency room with chest pain. Researchers tested new blood markers to see if they could diagnose heart attacks faster than current methods. The goal is to help doctors make quicker decisions and improve patient care.

This study tested whether a decision rule, combining the Marburg Heart Score with a rapid troponin blood test, can help general practitioners safely rule out serious heart problems in people with new chest pain. Over 900 adults with chest pain took part. The goal was to see if th…

This study tested whether a physical activity program delivered by mail and phone could help nearly 50,000 older women prevent heart attacks, strokes, falls, and hip fractures. Participants received exercise guides and tips to increase their daily activity. The goal was to see if…

This study tested an 8-week telephone-based stress management program for 153 women who had a heart attack and reported high stress. Participants were randomly assigned to either the stress program or enhanced usual care. The goal was to see if the program could lower stress and …

This study looked at whether having a 'patient partner' (a fellow heart attack survivor) work with a healthcare professional can help people stay physically active after completing cardiac rehab. 84 adults who had a heart attack and finished phase 2 rehab were split into two grou…

This study looked at 80 people who had a heart attack but no major blockages in their heart arteries (called MINOCA). Researchers wanted to see if a simple blood test ratio (white blood cell count divided by mean platelet volume) could predict short-term health problems after the…

This study looked at whether silent myocardial ischemia (reduced blood flow to the heart without symptoms) increases the risk of heart-related death or problems in people with coronary heart disease. Researchers followed participants for one to three years to track outcomes. The …

This study measured inflammation markers in the blood of 21 people who had a heart attack and compared them to heart damage seen on MRI scans. The goal was to understand how the body's inflammatory response relates to the size and type of heart injury. This research did not test …

This study looked at 12,500 cancer patients who had a type of heart attack called non-ST elevation myocardial infarction. Researchers compared two treatment approaches: invasive procedures like angiography and stenting versus medication-only care. The goal was to see which approa…

This study aimed to find genetic factors that might predict a complication called no-reflow, which can happen after a heart attack treatment to open blocked arteries. Researchers studied 80 adults who had a specific type of heart attack and had a procedure to restore blood flow. …

This study looked at 362 adults who had a heart attack to find out why they delayed going to the hospital. Researchers collected information on medical history, symptoms, and barriers like lack of awareness or transportation issues. The goal is to help doctors improve care and re…

This study looked at two methods for assigning care coordinators to older adults (65+) with heart disease or risk factors like diabetes and high blood pressure. The goal was to see which approach better prevented emergency room visits and hospitalizations. Researchers compared as…

This study tested new MRI methods to better detect bleeding inside heart muscle after a heart attack. Researchers studied 14 adults who had a heart attack to see if these scans could map the bleeding more clearly. The goal is to help doctors identify patients at higher risk for h…

This study tracked 11,000 COVID-19 patients to see how often they developed dangerous blood clots in arteries or veins. Researchers looked at risk factors, treatments, and outcomes over 30 and 90 days. The goal was to better understand and prevent these complications.

This small pilot study tested whether a heart rehab program that combines telehealth, home exercises, and a few clinic visits is practical for people who survived a heart attack. Ten participants were enrolled to compare this hybrid approach with traditional in-person rehab. The …

This study looked at 100 people who had a heart attack to see if certain signs of inflammation in the blood could predict who might die or develop heart failure within 6 months. Researchers measured these markers at several time points after the attack. The goal was to better und…

This study looked at whether taking acetaminophen (like Tylenol) can reduce aspirin's ability to prevent heart attacks. Researchers gave 55 healthy adults and smokers both drugs in different orders to see if timing matters. The goal was to understand if acetaminophen interferes w…

This study looked at 982 people who had a heart attack to see if things like air pollution, noise, and nearby parks or water affect their recovery one year later. Researchers used home addresses to measure environmental exposures. The goal is to understand which neighborhood fact…