MYOCARDIAL INFARCTION

This study tested the safety and effectiveness of a refined heart stent called Xience Sierra in a broad, real-world group of 1,757 patients. It focused on patients with various heart conditions, including many with diabetes or prediabetes, who are at higher risk for future heart …

This study tested whether giving doctors a computer decision-support tool helps patients get better cholesterol management after a heart attack. Over 1,100 patients at hospitals that either used the tool or followed standard care were compared. Researchers wanted to see if the to…

This study tested if a drug called Henagliflozin could help people who just had a major heart attack. About 240 patients who had emergency heart surgery (PCI) took the drug or a placebo for 6 months. Researchers checked if the drug reduced the amount of permanent heart damage and…

This study tested whether a virtual cardiac rehabilitation program delivered via a mobile app could improve patients' health more than standard in-person rehab. It involved 259 adults who recently had a heart attack, stent placement, or heart surgery. Researchers compared how far…

This study tested whether adding a very small dose of a clot-dissolving drug directly into the blocked heart artery during emergency heart attack treatment could improve blood flow to the heart muscle. The research involved 210 patients who had major heart attacks and were underg…

This study tested a new way to decide which older adults should get extra help from a care coordinator. Researchers wanted to see if asking people about their own difficulties managing care was better at preventing emergency room visits and hospital stays than the usual method, w…

This study tested whether an infusion of adult stem cells could help the heart heal better after a person's first heart attack. The goal was to see if this treatment could reduce the risk of developing heart failure later on. Researchers compared the stem cell infusion to a place…

This study aimed to find the safest rule for giving blood transfusions after major surgery to veterans at high risk for heart problems. It compared giving blood when hemoglobin drops below 10 (liberal strategy) versus waiting until it drops below 7 (restrictive strategy). The goa…

This study tested if a special, intensive follow-up program could help people better manage their health after a stroke or heart attack. It compared care from a team of nurses, doctors, and pharmacists working together to the usual follow-up care patients receive. The main goal w…

This study tested whether getting vitamin D levels to a healthy range could help prevent serious heart-related problems in people who recently had a heart attack. Over 600 participants were randomly assigned to either receive standard care or have their vitamin D levels carefully…

This study tested if a special laser treatment for gum disease could help control inflammation in the body, especially for people who have had a recent heart attack. Researchers compared standard gum cleaning with cleaning plus laser therapy. They measured gum health and blood ma…

This study tested whether giving iron directly into a vein (IV) works better than iron pills to improve heart muscle function in people recovering from a heart attack who also have low iron. About 300 patients were randomly assigned to receive either the IV iron or the pills duri…

This large study tested whether sending exercise guides and motivational tips through the mail could help older women become more active and improve their health. It enrolled nearly 50,000 women aged 60+ to see if this remote program could reduce serious health problems like hear…

This study tested if giving the drug atropine during an emergency heart attack procedure could prevent dangerous heart rhythm problems and low blood pressure. It involved 158 people having a specific type of heart attack (inferior STEMI) who were undergoing a procedure to open a …

This study tested whether adding the diabetes drug dapagliflozin improves recovery and prevents future heart problems in people with type 2 diabetes who recently had a heart attack. It involved 143 participants who received either the drug or a placebo. Researchers measured futur…

This study tested whether sending educational and supportive text messages could help people better manage their health in the year after a serious heart event. It involved 370 patients who had recently been hospitalized for a heart attack or similar condition. The goal was to se…

This study tested whether high-intensity interval training (HIIT) is better than standard moderate exercise for people recovering from a heart attack. 188 participants were randomly assigned to one of three 12-week exercise programs. Researchers measured changes in heart and lung…

This study tested a new device to remove blood clots during heart attack treatment. When doctors open blocked arteries with stents, clots can break apart and travel downstream, causing additional heart damage. Researchers compared a clot-trapping device (already used for strokes)…

This study tested a medical device that uses gentle sound waves (lithotripsy) to break up hard calcium deposits inside heart arteries. The goal was to safely open these hardened arteries so a stent could be placed more effectively. It involved 145 adults with coronary artery dise…

This small pilot study tested whether a new hybrid cardiac rehab program using telehealth could work for people recovering from a heart attack. The program mixed 5 in-clinic sessions with 19 home-based sessions over 12 weeks, aiming to make rehab more convenient. Researchers comp…

This study tested a new support program for clinics to improve care for adults with multiple long-term conditions like HIV, diabetes, and high blood pressure. Over 1,800 participants in South Africa either received standard care or the new ENHANCE program, which included special …

This study tested if a special support program could help people stay physically active after a heart attack. It involved 84 patients who had completed the main part of their cardiac rehab. The program paired patients with a 'patient partner'—a fellow survivor—and a healthcare pr…

This study tested a new decision-making tool for family doctors to use when a patient comes in with chest pain. The tool combines a simple checklist with a quick blood test to help doctors decide if a patient is likely having a heart attack and needs to go to the hospital. The go…

This study tested if a special type of CT scan could work as well as an MRI to check if heart muscle is still alive after a heart attack. Doctors need this information to decide if a procedure to reopen a blocked artery is worthwhile. The goal was to see if the CT scan could prov…

This study aimed to find faster ways to diagnose or rule out a heart attack in people arriving at the emergency room with chest pain. Researchers tested new blood markers that might work sooner than the current standard test, which can take hours to show results. They followed 10…

This study looked at whether environmental factors near a person's home affect their health one year after a heart attack. Researchers analyzed data from nearly 1,000 patients to see if air pollution, noise levels, or access to parks and nature influenced their risk of another he…

This study tested new MRI scanning methods to get clearer pictures of bleeding inside the heart muscle after a heart attack. Researchers enrolled 14 patients who had recently had a heart attack to see if these new scans could better identify damage and predict who might develop f…

This study investigated whether taking acetaminophen (like Tylenol) interferes with aspirin's ability to prevent blood clots that cause heart attacks. Researchers tested 55 healthy adults and smokers, giving them the drugs in different orders to see if timing matters. The goal wa…

This study aimed to find out if silent, painless episodes of reduced blood flow to the heart (silent ischemia) could predict future heart problems like heart attacks or death in people who already had coronary heart disease. Researchers followed 973 patients for one to three year…

This study aimed to understand how often and why dangerous blood clots occur in people with COVID-19. Researchers looked back at the health records of 11,000 patients who tested positive for COVID-19, tracking them for 90 days to see who developed clots, what treatments they rece…

This study aimed to find genetic markers that might predict a dangerous complication called 'no-reflow' or CMVO. This happens in some heart attack patients after a procedure to open a blocked artery, where blood still doesn't flow properly to the heart muscle. Researchers compare…

This study aimed to understand why people who have a heart attack often delay going to the hospital. Researchers surveyed 362 patients at a major hospital to identify common barriers, such as not recognizing symptoms or having trouble getting transportation. The goal is to use th…

This study aimed to understand how the body's inflammatory response after a heart attack relates to the amount of heart muscle damage. Researchers measured specific inflammation markers in the blood of 21 patients and compared them to detailed heart images from MRI scans taken a …

This study looked at whether simple blood test measurements could help predict how patients recover after a certain type of heart attack. Researchers followed 80 adults who had heart attacks despite having clear, non-blocked arteries. They checked if the ratio between white blood…

This study looked back at medical records to compare two approaches for treating heart attacks in people who also have cancer. Researchers examined whether invasive procedures (like stents) or medication-only treatment led to better survival and recovery for 12,500 patients. The …