Common painkiller may weaken Aspirin's heart attack protection

NCT ID NCT00646906

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at whether taking acetaminophen (like Tylenol) can reduce aspirin's ability to prevent heart attacks. Researchers gave 55 healthy adults and smokers both drugs in different orders to see if timing matters. The goal was to understand if acetaminophen interferes with aspirin's blood-thinning effects, which could affect how people with heart disease or arthritis manage their medications.

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Conditions

The condition(s) this trial relates to.

arthritic joint disease myocardial infarction Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital of The University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States