ARTHRITIS

This study is testing a new elbow joint implant called the Aptis PRUJ prosthesis. It is for people with painful, unstable conditions in a specific part of their elbow joint, often due to arthritis or past injury. The main goal is to see if the implant is safe and effective at imp…

This study is comparing two different surgical techniques for wrist arthritis caused by an old injury. It will involve 170 adults who need surgery to fuse some of their wrist bones. Researchers will measure grip strength, pain, and movement over a year to see if removing one smal…

This study is testing a new type of PET scan that uses much less radiation than current methods to detect bone problems. Researchers want to see if they can reduce radiation exposure by 10 to 100 times while still getting clear images of bone conditions like cancer, arthritis, an…

This study is testing a smart wearable device called gaitQ, which is worn on the legs. It uses gentle vibrations to help people with long-term movement conditions like Parkinson's, stroke, and multiple sclerosis improve their walking, reduce freezing episodes, and potentially low…

This study is testing whether group exercise classes over video calls are a practical and helpful way for veterans with knee or hip arthritis to stay active. It will enroll 50 inactive veterans to follow a 3-month exercise program, then a 6-month maintenance phase with text remin…

This pilot study is testing whether a minimally invasive procedure called geniculate artery embolization, when added to standard care (physical therapy and medications), provides better and longer-lasting pain relief for knee osteoarthritis than standard care alone. Researchers w…

This study is testing whether an experimental pill called dapansutrile can safely reduce the severe pain and swelling of a sudden gout attack. About 300 adults currently experiencing a gout flare-up will take either the study drug or a placebo pill twice a day for one week. Resea…

This study is testing whether a combination of herbal supplements and vitamin IV (intravenous) therapy can help reduce symptoms for people with conditions like anxiety, chronic pain, fibromyalgia, arthritis, and high blood pressure. It will enroll 25 participants to see if these …

This study is testing whether a new procedure using tiny, dissolvable beads injected into knee arteries works better than standard steroid injections for reducing arthritis pain. About 89 adults with moderate to severe knee osteoarthritis pain that hasn't improved with other trea…

This study aims to understand how daily pain, mood, and activities are connected by having 800 participants use a smartphone app called SOMA for four months. The goal is to find patterns that might predict when short-term (acute) pain becomes long-term (chronic) pain. A smaller g…

This study aims to understand the experiences of cancer patients who develop arthritis or muscle pain as side effects of immunotherapy. Researchers will interview 20 patients who developed these symptoms after cancer treatment. The goal is to learn how these side effects affect d…

This study aims to understand why rheumatic diseases, like arthritis, often affect minority communities more severely. It will observe 7,500 adults with known or suspected rheumatic conditions to gather information about their health. Participants will receive standard medical ca…

This study aims to learn more about the causes and long-term course of rare inflammatory diseases like systemic juvenile idiopathic arthritis (sJIA) and adult-onset Still's disease (AOSD). Researchers will follow up to 2000 children and adults with these conditions over time, col…

This study aims to understand why some people with spondyloarthritis (a type of inflammatory arthritis causing back and joint pain) develop more severe disease, while others do not. Researchers will observe up to 2,000 patients and some of their healthy relatives over time, using…