Iron showdown: IV vs pills after heart attack

NCT ID NCT05309499

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether giving iron through a vein (IV) works better than iron pills for improving heart pumping function in people who recently had a heart attack and also have low iron. About 300 adults took part, receiving either IV iron or oral iron. The main goal was to see if heart wall motion improved, which reflects better heart function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ferric carboxymaltose (IV iron) and ferrous sulphate (oral iron)

What this could lead to

If IV iron works better, it could become a standard way to help heart attack patients with low iron recover stronger heart function.

What could go wrong

This is a completed early-stage study with 298 people. The results may not apply to all patients, and iron therapy carries risks like allergic reactions or iron overload.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

iron deficiency anemia myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Kazan State Medical Universety

    Kazan', Tatarstan Republic, 420012, Russia