IRON-DEFICIENCY

This study tests whether giving intravenous (IV) iron before spinal fusion surgery can reduce the need for blood transfusions in teenagers with scoliosis who are also iron deficient. About 120 participants aged 10-19 will receive either IV iron or standard care. The goal is to se…

This study tests whether giving premature babies (born before 32 weeks) a drug called darbepoetin plus a slow-release intravenous iron can reduce the need for blood transfusions, keep iron levels healthy, and improve brain development. About 120 infants will be enrolled and compa…

This study looks at whether taking lactoferrin (a protein found in human milk) along with a small amount of iron can improve iron levels and exercise performance in women who exercise a lot and have low iron stores. About 30 women aged 18-45 will take either a low or high dose of…

This study will compare two types of iron (ferrous fumarate and ferrous bisglycinate) in daily prenatal vitamins for 172 pregnant women in Vancouver. The goal is to see which form better improves iron stores in the mother and baby, while also checking for side effects like consti…

This study looks at three types of iron supplements (low-dose, low-dose yeast-bound, and high-dose) in 36 female athletes aged 16–35 with low iron. Participants take their assigned supplement every other day for 12 weeks and complete fitness tests, blood draws, and gut bacteria s…

This study tests whether a special oral iron supplement (sucrosomial iron) can improve exercise ability and quality of life in people with chronic heart failure who also have low iron levels. About 60 participants will receive either the iron supplement or a placebo for several w…

This study tests whether a single dose of intravenous iron can improve exercise capacity in adults with a specific type of heart failure (HFpEF) who also have low iron levels. Researchers will measure changes in peak oxygen uptake during exercise tests over 12 weeks. The trial in…

This study tests whether giving iron through a vein can improve quality of life and walking ability in older adults who have iron deficiency and just had a heart valve replacement. About 402 participants will be randomly assigned to receive either iron infusions or standard care.…

This study tests whether giving iron through a vein can improve exercise ability and daily function in people with pulmonary hypertension (high blood pressure in the lungs) who also have low iron levels. Many patients with this condition have iron deficiency that oral supplements…

This study looks at how well young women with overweight or obesity absorb iron from their diet compared to women at a healthy weight. Researchers will track iron levels and losses over two years in 70 South African women. The goal is to understand why obesity raises the risk of …

This study uses MRI scans to see how iron moves to different organs like the heart, liver, and kidneys after an intravenous iron infusion. Researchers will follow 12 adults with iron deficiency for hours, days, and weeks after treatment. The goal is to learn more about iron stora…