Could a daily iron pill boost energy in heart failure?

NCT ID NCT06270498

Recruiting now Disease control Sponsor: Raffaele De Caterina Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a daily oral iron supplement (sucrosomial iron with vitamin C) can improve exercise ability and quality of life in people with chronic heart failure and iron deficiency. About 60 participants will receive either the iron supplement or a placebo for 24 weeks. Researchers will measure changes in a six-minute walk test and a heart failure symptom questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Sucrosomial iron (a type of iron supplement with vitamin C)
What this could lead to: If it works, this could offer a simple oral supplement to help heart failure patients feel better and walk farther.
What could go wrong: This is a small, early-phase trial with only 60 participants, so results may not apply broadly. Iron supplements can cause stomach upset or constipation.

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Conditions

The condition(s) this trial relates to.

congestive heart failure heart failure Iron Deficiencies iron deficiency anemia left ventricular failure Ventricular Dysfunction, Left

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC HEART FAILURE IRON-DEFICIENCY LEFT VENTRICULAR SYSTOLIC DYSFUNCTION

Contacts and locations

Locations

Azienda Ospedaliero Universitaria Pisana
RECRUITING

Pisa, Tuscany, 56124, Italy

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