CHRONIC HEART FAILURE

This study aims to monitor the long-term safety of the heart failure drug vericiguat in 1,400 Japanese patients over two years. Researchers will track side effects and compare how well the drug prevents heart-related deaths versus standard treatments. The study is observational, …

This study is testing whether a smartwatch-like device, combined with artificial intelligence, can help manage chronic heart failure. It aims to see if continuous remote monitoring can reduce hospital visits by 20% compared to standard doctor check-ups. About 205 adults with stab…

This trial is testing whether injecting stem cells from umbilical cords directly into the heart muscle during bypass surgery can help repair damage and improve heart function in people with chronic heart failure. The study will involve 51 participants who are already scheduled fo…

This study is testing a home monitoring device that automatically checks for leg swelling, a sign of worsening heart failure. It aims to see if sending alerts to a patient's care team when swelling is detected can help manage the condition better and prevent hospital visits. The …

This study is testing if adding the drug vericiguat to standard heart failure treatment helps improve the heart's structure and function. It will involve 60 adults with stable but weakened hearts who are already on standard medications. Researchers will compare those receiving th…

This study is testing a temporary heart pump called the iVAC 2L to see if it can help patients survive and recover better from high-risk stent procedures. The pump is inserted through a leg artery and helps the heart pump blood during the delicate surgery. Researchers will follow…

This study is testing whether implanting a special pacemaker, called Cardiac Resynchronization Therapy (CRT), can help patients who develop a specific heart rhythm problem after a minimally invasive aortic valve replacement (TAVI). The goal is to see if this early treatment can i…

This study is testing whether a program that combines physical exercise with brain training games can improve memory, thinking speed, and overall brain function in people living with chronic heart failure. Researchers will enroll 216 men and women to compare the combined program …

This study is testing if giving intravenous iron to hospitalized heart failure patients who also have low iron levels can improve their daily life and physical ability. It will involve 100 participants and compare those who receive the iron treatment to a control group. The main …

This study is testing if adding yoga to standard care can improve the quality of life for people with stable chronic heart failure. It will enroll 66 patients, who will be randomly assigned to either attend yoga classes or social activity workshops for three months. Researchers w…

This study is testing whether a special oral iron supplement can help people with chronic heart failure and iron deficiency feel better and be more active. Researchers will compare the supplement to a placebo (dummy pill) in 60 participants to see if it improves how far they can …

This study is testing whether an 8-week program of supervised strength training on exercise machines can help older adults who have both chronic heart failure and significant muscle loss (sarcopenia). Researchers will compare the training group to a group receiving usual care, me…

This study compares two different exercise programs for people with chronic heart failure. Researchers want to see whether shorter, high-intensity workouts or longer, high-intensity workouts work better to improve walking ability and quality of life. The study involves 45 partici…

This study compares two breathing support methods—high-flow oxygen therapy and non-invasive ventilation—to see which one better helps heart function in people with chronic heart failure. Researchers will measure how each method affects heart pressures and patient comfort in 30 pa…

This study aims to discover early warning signs that could predict future heart failure in people with type 2 diabetes. Researchers will follow 500 adults over 50 with diabetes but no known heart disease, performing yearly heart scans, blood tests, and walking tests. The goal is …

This study is collecting real-world safety information on finerenone, an approved heart failure medication, as it is used in routine medical practice in South Korea. Researchers will follow 300 adults with chronic heart failure for one year to monitor for any side effects and see…