CHRONIC HEART FAILURE
Clinical trials for CHRONIC HEART FAILURE explained in plain language.
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New heart failure drug shows promise in Mid-Stage trial
Disease control CompletedThis study tested a new medicine called AZD5462 in 375 adults with stable chronic heart failure. The goal was to see if the drug could improve how well the heart pumps blood. Participants took either the study drug or a placebo, and doctors measured heart function using ultrasoun…
Matched conditions: CHRONIC HEART FAILURE
Phase: PHASE2 • Sponsor: AstraZeneca • Aim: Disease control
Last updated May 17, 2026 07:05 UTC
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Could stem cells be the key to managing heart failure?
Disease control CompletedThis study tested a stem cell treatment (rexlemestrocel-L) in 565 adults with chronic heart failure. The goal was to see if injecting these cells into the heart could reduce serious heart events like hospitalizations or death. Participants were randomly assigned to receive either…
Matched conditions: CHRONIC HEART FAILURE
Phase: PHASE3 • Sponsor: Mesoblast, Inc. • Aim: Disease control
Last updated May 17, 2026 06:52 UTC
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Ultrasound zaps nerves to help failing hearts
Disease control CompletedThis study tested a device that uses ultrasound to calm overactive nerves in the kidneys, which can worsen heart failure. Six adults with chronic heart failure took part. The goal was to see if the procedure is safe and helps improve heart function.
Matched conditions: CHRONIC HEART FAILURE
Phase: NA • Sponsor: Otsuka Medical Devices Co., Ltd. Japan • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New diuretic protocol aims to improve heart failure care
Disease control CompletedThis study tested whether a structured plan for giving diuretics (water pills) to patients hospitalized with worsening chronic heart failure is safer and more effective than usual care. About 299 adults took part. The goal was to see if the protocol helped patients lose excess fl…
Matched conditions: CHRONIC HEART FAILURE
Phase: PHASE4 • Sponsor: University Hospital, Clermont-Ferrand • Aim: Disease control
Last updated May 05, 2026 11:54 UTC
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Acupuncture needles may boost heart function in failure patients
Symptom relief CompletedThis small study tested whether acupuncture could improve heart function and quality of life in 14 people with chronic heart failure. Participants received acupuncture treatments over 5 weeks, and researchers measured changes in heart pumping ability, walking distance, and sympto…
Matched conditions: CHRONIC HEART FAILURE
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Symptom relief
Last updated May 13, 2026 15:59 UTC
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Japanese heart failure patients under the microscope: Vericiguat's Real-World impact revealed
Knowledge-focused CompletedThis study looked at nearly 5,000 Japanese adults with chronic heart failure who started taking the drug vericiguat as part of their regular care. Researchers used hospital records to track outcomes like death, heart-related hospital stays, and how long patients stayed on the med…
Matched conditions: CHRONIC HEART FAILURE
Sponsor: Bayer • Aim: Knowledge-focused
Last updated May 17, 2026 06:51 UTC
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Vitamin d deficiency common in heart failure patients – but does supplementation help?
Knowledge-focused CompletedThis study looked at how common vitamin D deficiency is in people with chronic heart failure and whether taking vitamin D supplements improves their health. 91 adults with heart failure were divided into groups based on their vitamin D levels. Those with severe deficiency were ra…
Matched conditions: CHRONIC HEART FAILURE
Phase: PHASE4 • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Massive study reveals diabetes and weight swings predict heart failure survival
Knowledge-focused CompletedThis study looked at over 16,500 adults with chronic heart failure who were part of a remote monitoring program in France. Researchers wanted to see how having diabetes, other health conditions, and short-term weight changes were linked to survival. They used data already collect…
Matched conditions: CHRONIC HEART FAILURE
Sponsor: Satelia • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Nurse-led heart failure checkups aim to improve care and cut hospital visits
Knowledge-focused CompletedThis study looked at a new way of managing chronic heart failure using nurse-led consultations. The goal was to see how these visits help adjust medications and reduce hospital stays. Researchers analyzed data from 137 patients over 12 months. The findings may help improve care f…
Matched conditions: CHRONIC HEART FAILURE
Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC