Heart scan may predict who benefits from pacemaker therapy
NCT ID NCT03667989
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a special heart scan (SPECT) can predict which people with severe chronic heart failure will improve after getting a cardiac resynchronization therapy device. The scan uses a radioactive tracer to measure nerve activity in the heart. Researchers enrolled 60 patients and checked if the scan could tell who would have a significant reduction in heart size after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
123I-MIBG (a radioactive tracer used in SPECT imaging)
What this could lead to
If successful, this could help doctors identify which heart failure patients are most likely to benefit from cardiac resynchronization therapy, avoiding unnecessary procedures.
What could go wrong
This is a small, completed study with only 60 participants. The imaging technique may not reliably predict therapy response in broader populations.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cardiology Research Institute, Tomsk NRMC
Tomsk, Tomsk Oblast, 634012, Russia