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Can a diabetes drug tame chronic heart failure? a Real-World study investigates

NCT ID NCT05236673

Completed Disease control Sponsor: Boehringer Ingelheim Source: ClinicalTrials.gov ↗

First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time

Summary

This study observes Korean adults with chronic heart failure (NYHA class II-IV) who are starting Jardiance (empagliflozin) for the first time. The main goal is to track the drug's safety in everyday clinical practice, including any side effects or serious reactions. Researchers will also look at whether the drug reduces hospitalizations for heart failure. This is an observational study, meaning participants receive standard care and no experimental treatment is given.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
empagliflozin (Jardiance), a 10mg tablet taken by mouth
What this could lead to
If this study shows that empagliflozin is safe and effective in Korean patients with chronic heart failure, it could support its continued use in routine care for this population.
What could go wrong
This is an observational study, not a controlled trial, so it cannot prove cause and effect. The results may be influenced by other factors, and the safety monitoring may not capture all rare or long-term side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

congestive heart failure heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE

Contacts and locations

Locations

  • Asan Medical Center

    Seoul, 05505, South Korea

  • Chonnam National University Hospital)

    Gwangju, 61469, South Korea

  • Chungnam National University Hospital

    Daejeon, 35015, South Korea

  • Dongguk University Medical Center

    Goyang-si, Gyeonggi-do, 10326, South Korea

  • Hallym University Medical Center

    Anyang-si, Gyeonggi-do, 14068, South Korea

  • Inje University Busan Paik Hospital

    Busan, 47392, South Korea

  • Inje University Haeundae Paik Hospital

    Busan, 48108, South Korea

  • Inje University Ilsan Paik Hospital

    Goyang-si, Gyeonggi-do, 10380, South Korea

  • Jeonbuk National University Hospital

    Jeonju-si, Jeollabuk-do, 54907, South Korea

  • Kangwon National University Hospital

    Chuncheon-si, Gangwon-do, 24289, South Korea

  • Korea University Anam Hospital

    Seoul, 02841, South Korea

  • Kyungpook National University Hospital

    Daegu, 41944, South Korea

  • Pusan National University Hospital

    Busan, 49241, South Korea

  • Pusan National University Yangsan Hospital

    Busan, 50612, South Korea

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Seoul National University Boramae Medical Center

    Seoul, 07061, South Korea

  • Severance Hospital, Yonsei University Health System

    Seoul, 03722, South Korea

  • The Catholic University of Korea, Seoul ST. Mary's Hospital

    Seoul, 06591, South Korea

  • The Catholic University of Korea, Uijeongbu ST. Mary's Hospital

    Uijeongbu-si, Gyeonggi-do, 11765, South Korea

  • VHS Medical Center

    Seoul, 05368, South Korea

  • Yeungnam University Medical Center

    Daegu, 42415, South Korea

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