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Exercise order may boost heart function in heart failure patients

NCT ID NCT06626542

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether doing resistance or aerobic exercise first during a rehab session affects heart function in men with chronic heart failure. Sixty men aged 55-65 with reduced heart pumping ability took part. Researchers measured heart function and quality of life to see if the sequence made a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
resistance and aerobic training exercises
What this could lead to
If the sequence matters, it could help design better cardiac rehab programs to improve heart function and quality of life in heart failure patients.
What could go wrong
This is a small, completed study with only 60 male participants, so results may not apply to women or all heart failure patients. The exercise order may not produce a clear benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Sep 2023

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

55 to 65 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male patients with chronic heart failure and ages from 55 to 65 years old. * Class II and class III heart failure according to NYHA classification. * HFrEF category with LVEF \<40% as documented by echocardiogram within \<6 months. * Receiving the same medical treatment programme for at least 3 months. * Having a close level of functional capacity assessed by 6 minute walking test Exclusion Criteria: * • Uncontrolled atrial fibrillation. * Diabetes mellitus. * Myocardial infarction or recurrent angina within \<3 months. * Patients with chronic chest diseases. * Severe stenotic valvular disease. * Clinically significant peripheral vascular disease. * Exercise-induced angina, ST segment changes or exercise induce AV block. * Patients with chronic renal failure. * Any cognitive impairment that interferes with prescribed exercise procedures. * Musculoskeletal or neurological limitation to physical exercise.

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Conditions

The condition(s) this trial relates to.

congestive heart failure heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Heart failure

Contacts and locations

Locations

  • National Heart Institute

    Giza, Agouza Giza Governorate, 12511, Egypt

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