Can two old drugs beat heart failure? new study aims to find out
NCT ID NCT03514108
First seen Jan 04, 2026 · Last updated Apr 29, 2026 · Updated 21 times
Summary
This study tested two drugs—hydralazine-ISDN and metformin—in 1,100 people with chronic heart failure and reduced heart function. The goal was to see if these drugs could lower the risk of death or hospital stays due to worsening heart failure. Participants took either the study drugs or a placebo, and researchers tracked their health over time.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Aalborg University Hospital
Aalborg, Denmark
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Aarhus University Hospital
Aarhus, Denmark
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Amager Hospital
Copenhagen, Denmark
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Bispebjerg Hospital
Copenhagen, Denmark
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Gentofte Hospital
Copenhagen, Denmark
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Glostrup Hospital
Copenhagen, Denmark
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Herlev Hospital
Copenhagen, Denmark
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Herning Hospital
Herning, Denmark
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Holbæk Hospital
Holbæk, Region Sjælland, Denmark
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Holbæk Hospital
Holbæk, Denmark
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Horsens Hospital
Horsens, Denmark
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Hvidovre Hospital
Copenhagen, Denmark
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Kolding Hospital
Kolding, Denmark
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Nordsjællands Hospital Hillerød
Hillerød, Denmark
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Nykøbing Falster Hospital
Nykøbing Falster, Denmark
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Odense University Hospital
Odense, Denmark
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Randers Hospital
Randers, Denmark
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Regionshospital Nordjylland, Hjørring
Hjørring, Denmark
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Rigshospitalet
Copenhagen, Denmark
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Silkeborg Hospital
Silkeborg, Denmark
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Sjællands Universitetshospital, Roskilde
Roskilde, Denmark
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Slagelse Sygehus
Slagelse, Denmark
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Sydvestjysk Sygehus, Esbjerg
Esbjerg, Denmark
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Sygehus Sønderjylland, Aabenraa
Aabenraa, Denmark
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Vejle Hospital
Vejle, Denmark
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Viborg Hospital
Viborg, Denmark
Conditions
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