Iron infusion trial aims to boost exercise in lung disease patients

NCT ID NCT07359599

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving iron through a vein can help people with pulmonary hypertension (high blood pressure in the lungs) who also have low iron levels. Many patients with this condition have trouble absorbing iron from pills. The trial will compare intravenous iron to a placebo in 306 participants, measuring how far they can walk in six minutes and their quality of life after 24 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ferric carboxymaltose (intravenous iron)
What this could lead to
If it works, this could offer a new way to improve exercise capacity and quality of life for many pulmonary hypertension patients who also have iron deficiency.
What could go wrong
This is a phase 4 trial, but it's still uncertain whether correcting iron deficiency will actually improve symptoms. The study is relatively small and the effect may be modest or absent.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AZ Groeninge

    NOT_YET_RECRUITING

    Kortrijk, 8500, Belgium

    Contact Email: •••••@•••••

  • AZORG

    NOT_YET_RECRUITING

    Aalst, 9300, Belgium

  • CHU Charleroi-Chimay

    NOT_YET_RECRUITING

    Lodelinsart, 6042, Belgium

  • CHU UCL Namur

    NOT_YET_RECRUITING

    Yvoir, 5530, Belgium

  • Hôpital Erasme

    NOT_YET_RECRUITING

    Brussels, 1070, Belgium

  • UZ Leuven

    NOT_YET_RECRUITING

    Leuven, 3000, Belgium

  • Ziekenhuis Oost-Limburg

    RECRUITING

    Genk, 3600, Belgium

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