Which breathing setting keeps Kids' lungs healthier during heart surgery?
NCT ID NCT07754591
First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time
Summary
This trial asks whether one way of setting a breathing machine is better than another for children born with a hole in the heart who are having surgery to close it. The hole lets extra blood flow to the lungs, which can make them stiff and harder to inflate. During surgery, a machine breathes for the child, and it can be set to control either the pressure or the volume of each breath. Researchers are comparing these two settings to see which keeps the lungs easier to inflate and lets air move more freely through the breathing tubes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Pressure-controlled ventilation (PCV) compared with volume-controlled ventilation (VCV) during mechanical ventilation in pediatric heart surgery
- What this could lead to
- If one setting proves better, it could guide safer breathing support for children during heart surgery, potentially improving lung function and recovery.
- What could go wrong
- This is a small, early-stage comparison in a specific group of children, so results may not apply broadly. Both settings are standard, and differences may be minor.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Nil Ratan Sircar Medical College and Hospital
Kolkata, West Bengal, 700014, India
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