Iron shots after valve surgery: could they boost energy and walking ability?
NCT ID NCT07370688
First seen Jun 25, 2026 · Last updated Jun 25, 2026
Summary
This study tests whether giving iron infusions after a minimally invasive heart valve replacement (TAVI) helps patients with aortic stenosis and iron deficiency feel better and walk farther. About 402 older adults will be randomly assigned to receive iron or standard care. Researchers will measure quality of life and exercise capacity 24 weeks after the procedure.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Erasmus University Medical Center
RECRUITINGRotterdam, South Holland, 3015 GD, Netherlands
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ferric carboxymaltose (iron infusion)
What this could lead to
If it works, this could show that correcting iron deficiency after TAVI helps patients feel better and walk farther.
What could go wrong
This is a Phase 4 trial, but the benefit of iron in this setting is not proven. Some patients may not improve, and iron infusions carry rare risks like allergic reactions.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.