Erasmus Medical Center

This study is testing two different orders of intensive pre-surgery treatments for people with a type of esophageal cancer that has spread to nearby lymph nodes. The goal is to see if combining two established chemotherapy and radiation regimens before surgery can better control …

This study aims to find out which of two common medications works better for children with moderate-to-severe alopecia areata, a condition causing patchy or total hair loss. Children and teens (ages 2-17) starting their first systemic treatment will choose, with their parents, to…

This study tests if adding a small balloon pump (IABP) to a major heart-lung support machine (VA ECMO) helps patients with severe heart failure recover enough to be safely taken off the machine. It will involve 430 adults in cardiogenic shock who are on this advanced life support…

This study is testing if it's practical for certain hospitalized patients to be sent home early and continue their care through a 'Virtual Ward.' Patients would be monitored remotely from home using a smartphone app to track their vital signs and symptoms. The main goal is to see…

This study is testing whether a home monitoring program can replace half of the regular hospital visits for people with pulmonary fibrosis. 220 participants will be randomly assigned to either continue standard hospital care or use a home kit with weekly breathing tests, symptom …

This study is testing how long a new, targeted electrical pulse treatment keeps a common heart rhythm problem (paroxysmal atrial fibrillation) from coming back. Twenty patients will get the treatment, and then have a planned second procedure 2-3 months later to check if the treat…

This study is testing if adding a special program to manage sleep and stress helps people recover better from heart problems. It will involve 200 adults already enrolled in standard cardiac rehabilitation who report issues with sleep or stress. Half will get the standard rehab, a…

This study is testing whether a simple finger-prick blood test can reliably detect tiny pieces of cancer DNA in the blood. Researchers want to see if this at-home method works as well as traditional blood draws from the arm for monitoring patients with colorectal cancer that has …

This study is testing a new tool called SCALE-EYE that helps doctors measure colon polyps more accurately during colonoscopy procedures. Researchers will compare SCALE-EYE's measurements against current methods in about 241 people aged 55-80 who are having routine colonoscopies. …

This study is testing a new, faster bedside blood test for trauma patients with severe bleeding. The goal is to see if this quick test can be used during emergency care to measure a key clotting protein called fibrinogen in just a few minutes, instead of the usual 30-45 minutes. …

This study is testing whether a simple, non-drug treatment called bright light therapy can help reduce feelings of depression in adults with intellectual disabilities. The researchers are working with care organizations to see how practical and acceptable this therapy is for both…

This study is testing whether a home-based computer brain training program can help people recovering from brain injuries like stroke. Thirty adults currently in outpatient rehab will try a 5-week program that mixes online brain exercises at home with some in-person sessions. Res…

This study is testing whether listening to music during and after electroconvulsive therapy (ECT) can reduce agitation when patients wake up. Researchers will enroll 92 adults with severe depression who are receiving ECT treatment. They want to see if this simple, side-effect-fre…

This study is testing whether giving iron infusions to older patients with iron deficiency after a minimally invasive heart valve replacement (TAVI) helps them feel better and walk farther. Researchers will compare patients who receive iron infusions to those who receive standard…

This study is testing whether a 12-week, home-based high-intensity interval training program can improve exercise capacity in teens and adults (ages 12-45) born with specific heart defects that required surgery to create a connection between the heart's right ventricle and lung a…

This study aims to map the natural progression of CAMK2-related neurodevelopmental disorders, which are extremely rare genetic conditions affecting brain development. Researchers will collect detailed information from 150 children and adults worldwide who have specific CAMK2 gene…

This study aims to create a standard questionnaire to better measure the success of dental implants. It will ask 1000 patients and their dentists about their experiences and clinical results at several points during treatment. The goal is to combine patient feedback with medical …

This study aims to act as an early warning system for new or changing respiratory viruses. Researchers will regularly test 250 healthcare and animal workers in the Netherlands, whether they feel sick or not, to spot infections early. The goal is to understand how viruses spread a…

This study aims to understand a puzzling effect of measles: the virus provides lifelong protection against itself but also weakens the immune system's memory of other diseases for years, a phenomenon called 'immune amnesia.' Researchers will recruit 300 adults, including people w…