Can a smarter ventilator ease breathing for asthma and COPD patients?

NCT ID NCT06563544

Recruiting now Disease control Sponsor: Erasmus Medical Center Source: ClinicalTrials.gov ↗

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This pilot study explores whether a newer ventilation method called flow-controlled ventilation (FCV) can help intubated patients with asthma or COPD exacerbations breathe with less effort compared to standard volume-controlled ventilation (VCV). Ten adult patients on mechanical ventilators will receive both ventilation modes in random order, each for 90 minutes. The main goal is to see if FCV lowers the minute volume needed, which could mean gentler and more efficient breathing support.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Flow-controlled ventilation (FCV), a new mode of mechanical ventilation
What this could lead to: If FCV works as hoped, it could make breathing support gentler and more efficient for people with severe asthma or COPD flare-ups.
What could go wrong: This is a very small pilot study with only 10 patients, so results may not apply broadly. The new ventilation mode might not reduce breathing effort as expected or could cause discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ASTHMA COPD are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acute asthma obstructive lung disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA COPD MECHANICAL VENTILATION PRESSURE HIGH OBSTRUCTIVE PULMONARY DISEASE

Contacts and locations

Locations

Erasmus Medical Center
RECRUITING

Rotterdam, South Holland, 3015 GD, Netherlands
Maasstad Hospital
RECRUITING

Rotterdam, South Holland, 3079DZ, Netherlands

More trials for these conditions

Other studies related to the condition(s) this trial covers.