Acute asthma

This study is testing a mobile app called Adhera Caring Digital Program for Obesity (ACDP-O) in 280 families. The app provides personalized education, mental health monitoring, and wearable device integration to support weight management and well-being in adolescents and young ad…

This study will give HEPA air cleaners to 55 children (ages 7-18) with asthma living in low-income housing in East Harlem, NYC. Researchers will measure indoor air pollution and track asthma attacks, lung function, and airway inflammation over a year. The goal is to see if a simp…

This study tests whether giving adults with acute asthma a specific rescue inhaler (Airsupra) right in the emergency department can reduce the chance of another asthma attack within 3 months. About 1,860 participants will either receive Airsupra or continue usual care. The goal i…

This study tests a personalized smoking cessation program for smokers admitted to the hospital with heart or lung disease. Participants receive tailored medication, counseling, and text message support to help them quit and stay smoke-free. The goal is to see if this approach lea…

This study tests whether azithromycin, an antibiotic, can reduce airway inflammation in children ages 3-17 hospitalized for critical asthma. One hundred participants will receive the drug for three days while researchers monitor inflammation markers and side effects. The goal is …

This study tests two ways to prevent asthma attacks: using inhaled steroids as a rescue inhaler (R-ICS) or taking azithromycin regularly. Researchers want to see which works better, alone or together, for people with poorly controlled asthma. About 3,200 people aged 13-75 with as…

This study tests a small wearable device called AeviceMD that listens to lung sounds and detects wheezing. Researchers want to see if the device is as accurate as a doctor using a stethoscope. About 160 children and adults with asthma will participate. If successful, the device c…

This study compares two different doses of the steroid dexamethasone (0.3 mg/kg vs. 0.6 mg/kg) given by mouth to children aged 4-15 who come to the emergency department with an asthma attack. The goal is to see which dose works better at reducing the need for another steroid pres…

This study tests whether giving intravenous magnesium (IVMg) early to children aged 2-17 with severe asthma in the emergency room can reduce their breathing distress more than a placebo. About 192 children who still have moderate-to-severe symptoms after initial treatment will re…

This study looks at how short-term exposure to air pollution affects children's breathing. Around 330 children from London schools will either take a science lesson or do physical education outdoors. Researchers will measure lung function and immune responses to see if exercising…

This study aims to see if analyzing the chemicals in a child's breath can help diagnose and monitor diseases like asthma, neurological disorders, and type 1 diabetes. Researchers will collect breath samples from up to 3,600 children and teens to find patterns linked to these cond…

This study is looking for 530 adults with hay fever in South-Eastern Australia to help create a tool that predicts thunderstorm asthma. Participants will have allergy and lung function tests, then track their symptoms during spring for two years. The goal is to find warning signs…

This study looks at whether a new way of organizing hospital care, called an Acute Medical Unit, can help older adults with sudden illnesses like infections or COPD get better faster and spend fewer days in the hospital. Researchers will compare 220 patients who receive this new …

This study tests a soft, wearable stethoscope that can continuously listen to a child's breathing and detect wheezing, a sign of an asthma attack. Researchers at Emory University will enroll 25 children hospitalized for asthma to wear the device for up to 8 hours. The goal is to …

This observational study enrolls 500 children aged 6-17 who come to the emergency department with an acute asthma attack. Researchers will check if doctors follow the latest GINA 2025 guidelines for diagnosis, treatment, and follow-up. The goal is to see if standardizing care imp…

This study tests whether computer-based decision support tools can help doctors reduce unnecessary antibiotic use in children with lower respiratory tract infections like pneumonia, bronchiolitis, and asthma flare-ups. Most of these infections are caused by viruses, not bacteria,…

This study will enroll 900 children aged 5-17 with asthma to see if remote monitoring—using routine health data and a smartphone app—can predict asthma attacks. Researchers will track whether this system reduces the number of attacks compared to past averages. A subset of high-ri…