Asthma attack study seeks best steroid dose for kids

NCT ID NCT07402707

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two different doses of the steroid dexamethasone (0.3 mg/kg vs. 0.6 mg/kg) given by mouth to children aged 4-15 who come to the emergency department with an asthma attack. The goal is to see which dose works better at reducing the need for another steroid prescription within two weeks. The study will also track how often children need to return to the ER or see a doctor, and how well parents and kids tolerate the treatment. It is a small pilot study designed to gather information for a larger, more definitive trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

dexamethasone

What this could lead to

If successful, this could help determine the most effective dose of dexamethasone for children with asthma attacks, potentially reducing repeat steroid prescriptions and ER visits.

What could go wrong

This is a small pilot study (104 children) focused on feasibility, not definitive results. The two doses may show no clear difference, and a larger trial is needed to confirm any findings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute asthma status asthmaticus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sheffield Children's NHS Foundation Trust

    RECRUITING

    Sheffield, S10 2TH, United Kingdom

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••