Wrist surgery pain relief showdown: which block works best?

NCT ID NCT07665762

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two ways to numb the arm for wrist fracture surgery in people at high risk for severe pain. One method uses a long-acting numbing drug (liposomal bupivacaine) plus regular bupivacaine, and the other uses a steroid (dexamethasone) plus regular bupivacaine. The goal is to see which provides better pain control in the first 48 hours after surgery. About 90 adults with risk factors like severe pre-surgery pain or anxiety will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Liposomal bupivacaine and dexamethasone

What this could lead to

If successful, this could show that one pain-block method works better for high-risk patients, helping doctors choose the most effective and cost-efficient option.

What could go wrong

This is a small, early-stage trial with only 90 participants, so results may not apply to everyone. The difference between treatments might be small or not clinically meaningful.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Pain Pain, Postoperative radius fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Queen Mary Hospital

    Hong Kong, Hong Kong

    Contact Phone: •••-•••-•••• Email: •••••@•••••