Wrist surgery pain relief showdown: which block works best?

NCT ID NCT07665762

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two ways to numb the arm for wrist fracture surgery in people at high risk for severe pain. One method uses a long-acting numbing drug (liposomal bupivacaine) plus regular bupivacaine, and the other uses a steroid (dexamethasone) plus regular bupivacaine. The goal is to see which provides better pain control in the first 48 hours after surgery. About 90 adults with risk factors like severe pre-surgery pain or anxiety will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Liposomal bupivacaine and dexamethasone
What this could lead to
If successful, this could show that one pain-block method works better for high-risk patients, helping doctors choose the most effective and cost-efficient option.
What could go wrong
This is a small, early-stage trial with only 90 participants, so results may not apply to everyone. The difference between treatments might be small or not clinically meaningful.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DEXAMETHASONE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Pain Pain, Postoperative radius fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Queen Mary Hospital

    Hong Kong, Hong Kong

More trials for these conditions

Other studies related to the condition(s) this trial covers.